Title:
LACTOBACILLUS PENTOSUS CAPABLE OF RELIEVING PATHOLOGICAL FEATURES OF MICE INFECTED WITH INFLUENZA VIRUSES AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/185569
Kind Code:
A1
Abstract:
Lactobacillus pentosus CCFM1227 capable of relieving pathological features of mice infected with influenza viruses and the use of same in preparation of related products. A product prepared by means of the Lactobacillus pentosus CCFM1227 can improve the innate immune response of mice infected with influenza viruses, thereby preventing and/or relieving influenza virus infection, which comprise relieving body weight loss, decreasing the total protein level of alveolar lavage fluid, reducing lung inflammation infiltration, reducing lung viral load, decreasing the lung IL-6 level and increasing the lung IFN-β level of mice infected with influenza viruses. The Lactobacillus pentosus CCFM1227 can ferment phloretin to produce desaminotyrosine.
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Inventors:
LU WENWEI (CN)
WANG QIANWEN (CN)
ZHAO JIANXIN (CN)
WANG HONGCHAO (CN)
MA SHENYAN (CN)
CHEN WEI (CN)
ZHANG HAO (CN)
WANG QIANWEN (CN)
ZHAO JIANXIN (CN)
WANG HONGCHAO (CN)
MA SHENYAN (CN)
CHEN WEI (CN)
ZHANG HAO (CN)
Application Number:
PCT/CN2023/083004
Publication Date:
October 05, 2023
Filing Date:
March 22, 2023
Export Citation:
Assignee:
UNIV JIANGNAN (CN)
International Classes:
C12N1/20; A23C9/123; A23C9/13; A23L11/50; A23L19/00; A23L29/00; A23L33/135; A61K35/747; A61P31/16; C12R1/225
Domestic Patent References:
| WO2012133827A1 | 2012-10-04 |
Foreign References:
| CN114657100A | 2022-06-24 | |||
| CN101031313A | 2007-09-05 | |||
| CN113785986A | 2021-12-14 | |||
| CN109486722A | 2019-03-19 | |||
| JP2010227043A | 2010-10-14 |
Attorney, Agent or Firm:
HARBIN SHINEIP INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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