LATERAL FLOW ASSAY DEVICE FOR TRAUMATIC BRAIN INJURY DIAGNOSIS USING TIME-RESOLVED FLUORESCENCE ANALYSIS, AND METHOD FOR DIAGNOSING TRAUMATIC BRAIN INJURY BY USING SAME

WIPO Patent Application WO/2021/201350

A1

A lateral flow assay device for detecting a traumatic brain injury marker according to an embodiment of the present invention comprises: a sample pad into which a blood sample containing a traumatic brain injury marker is injected; an adsorption pad comprising a probe which is mixed with the marker when the traumatic brain injury marker migrates from the sample pad, to form a traumatic brain injury marker complex; and a porous membrane which is in fluid communication with the adsorption pad and allows capillary movement of the traumatic brain injury marker complex from the adsorption pad to a detection line, wherein the probe comprises: capture antibodies consisting of antibodies labeled with a specific binding material that specifically binds to the traumatic brain injury marker; and detector antibodies consisting of antibodies labeled with a fluorescent material with a relatively long emission lifetime of 1 microsecond or greater, and, as the antibodies labeled with a specific binding material or a fluorescent material, a mixture of antibodies derived from at least two different species is used.

JP2000506378	Description: Polymer Films, Assays and Methods for Direct Color Detection of Analite.
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WO/2019/208711	PARTICLE AND PRODUCTION METHOD THEREFOR

KANG JONGEUN (KR)
HWANG KYU-YOUN (KR)
PARK JONG-MYEON (KR)
KIM HANSHIN (KR)

PCT/KR2020/012035

October 07, 2021

September 07, 2020

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PREC BIOSENSOR INC (KR)

G01N33/543; G01N33/558; G01N33/58; G01N33/68

KR20050062531A	2005-06-23
JP2016533499A	2016-10-27
KR20120132249A	2012-12-05
KR20190117350A	2019-10-16
JP2017509902A	2017-04-06
KR20180025295A	2018-03-08

See also references of EP 3916387A4

YOU ME PATENT AND LAW FIRM (KR)

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