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Title:
LENTIVIRAL VECTOR COMPOSITIONS AND METHODS OF USE
Document Type and Number:
WIPO Patent Application WO1999061598
Kind Code:
A3
Abstract:
Disclosed are lentiviral vector compositions and methods of use.

Inventors:
CHANG LUNG-JI (US)
CUI YAN (US)
IWAKUMA TOMOO (US)
Application Number:
PCT/US1999/011634
Publication Date:
April 13, 2000
Filing Date:
May 26, 1999
Export Citation:
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Assignee:
UNIV FLORIDA (US)
CHANG LUNG JI (US)
CUI YAN (US)
IWAKUMA TOMOO (US)
International Classes:
C12N15/867; (IPC1-7): C12N15/66; C12N5/10; C12N15/86
Domestic Patent References:
WO1992007943A11992-05-14
WO1997036481A11997-10-09
WO1997007225A21997-02-27
Foreign References:
US5436146A1995-07-25
Other References:
L. NALDINI ET AL.: "Efficient tranfer, intergration and sustained long-term expression of the transgene in adult rat brain injected with a lentiviral vector", PNAS, vol. 93, 1996, pages 11382 - 11388, XP002130632
L. NALDINI ET AL.: "In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector", SCIENCE, vol. 272, no. 5259, 1996, pages 263 - 267, XP000583652
P. CORBEAU ET AL.: "Efficient gene transfer by a HIV-1-derived vector utilizing a stable packaging cell line", PNAS, vol. 93, 1996, pages 14070 - 14075, XP000872865
R. CARROLL ET AL.: "A HIV-1-based retroviral vector system utilizing stable HIV-1 packaging cell lines", JOURNAL OF VIROLOGY, vol. 68, no. 9, 1994, pages 6047 - 6051, XP002063697
V. NARRY KIM ET AL.: "Minimal requirement for a lentivirus vector based on human HIV-1", JOURNAL OF VIROLOGY, vol. 72, no. 1, 1998, pages 811 - 816, XP000872453
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