Title:
LIFESPAN-EXTENDING AGENT
Document Type and Number:
WIPO Patent Application WO/2010/104056
Kind Code:
A1
Abstract:
Disclosed is a lifespan-extending agent which can inhibit senility caused by aging in individuals, is effective on the maintenance of homeostasis in living bodies, and can extend a lifespan in a safe manner even when ingested continuously for a long period. Specifically disclosed is a lifespan-extending agent, an anti-aging agent, or a Klotho protein expression enhancer comprising activated charcoal as an active ingredient. The lifespan-extending agent, the anti-aging agent or the Klotho protein expression enhancer has substantially no adverse side effect and can extend a lifespan when administered in the form of an oral preparation.
Inventors:
GOTO SUMIE (JP)
YOSHIOKA NAOKI (JP)
NISHIJIMA FUYUHIKO (JP)
NIWA TOSHIMITSU (JP)
YOSHIOKA NAOKI (JP)
NISHIJIMA FUYUHIKO (JP)
NIWA TOSHIMITSU (JP)
Application Number:
PCT/JP2010/053841
Publication Date:
September 16, 2010
Filing Date:
March 09, 2010
Export Citation:
Assignee:
UNIV NAGOYA NAT UNIV CORP (JP)
GOTO SUMIE (JP)
YOSHIOKA NAOKI (JP)
NISHIJIMA FUYUHIKO (JP)
NIWA TOSHIMITSU (JP)
GOTO SUMIE (JP)
YOSHIOKA NAOKI (JP)
NISHIJIMA FUYUHIKO (JP)
NIWA TOSHIMITSU (JP)
International Classes:
A61K33/44; A61P43/00
Domestic Patent References:
WO2006123618A1 | 2006-11-23 | |||
WO2004089384A1 | 2004-10-21 |
Foreign References:
JPH1129485A | 1999-02-02 | |||
JP2005314415A | 2005-11-10 | |||
JPH06135841A | 1994-05-17 | |||
JP2008174473A | 2008-07-31 |
Other References:
TOMOHIRO KATSUYA ET AL.: "Roka Kanren Idenshi to Kokarei Igaku", JAPANESE JOURNAL OF GERIATRICS, vol. 45, no. 2, 2008, pages 141 - 144
HIROTAKA CHIKUDA ET AL.: "Klotho Idenshi ni yoru Kotsutaisha Chosetsu", THE BONE, vol. 20, no. 5, 2006, pages 77-637 - 81-641
URAKAWA,I ET AL.: "Klotho converts canonical FGF receptor into a specific receptor for FGF23", NATURE, vol. 444, no. 7120, 2006, pages 770 - 774
HIROTAKA CHIKUDA ET AL.: "Klotho Idenshi ni yoru Kotsutaisha Chosetsu", THE BONE, vol. 20, no. 5, 2006, pages 77-637 - 81-641
URAKAWA,I ET AL.: "Klotho converts canonical FGF receptor into a specific receptor for FGF23", NATURE, vol. 444, no. 7120, 2006, pages 770 - 774
Attorney, Agent or Firm:
MORITA Kenichi et al. (JP)
Ken-ichi Morita (JP)
Ken-ichi Morita (JP)
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