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Title:
LIGHT-RESPONSIVE NUCLEOTIDE MOLECULE, AND METHOD FOR PRODUCTION OF LIGHT-RESPONSIVE MODIFIED NUCLEIC ACID BY USING THE LIGHT-RESPONSIVE NUCLEOTIDE MOLECULE
Document Type and Number:
WIPO Patent Application WO/2010/013442
Kind Code:
A1
Abstract:
Disclosed are: a method for producing a long-chain light-responsive modified nucleic acid without the need of employing any DNA synthesizer; and a light-responsive artificial nucleotide molecule for use in the method. Specifically disclosed are: a light-responsive α-dideoxyribonucleotide   having a light-responsive α- dideoxyribonucleoside as a nucleoside moiety; and a method for producing a light-responsive modified nucleic acid by introducing the light-responsive α-dideoxyribonucleotide into a nucleic acid.

Inventors:
FUJIMOTO KENZO (JP)
OGINO MASAYUKI (JP)
NITTA YUKARI (JP)
Application Number:
PCT/JP2009/003540
Publication Date:
February 04, 2010
Filing Date:
July 28, 2009
Export Citation:
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Assignee:
JAPAN ADV INST SCIENCE & TECH (JP)
SC WORLD INC (JP)
FUJIMOTO KENZO (JP)
OGINO MASAYUKI (JP)
NITTA YUKARI (JP)
International Classes:
C07H19/06; C07H19/14; C07H21/02; C07H21/04; C12P19/34; C12N15/09
Foreign References:
JP2005350386A2005-12-22
JPS63241356A1988-10-06
Other References:
MASAYUKI OGINO ET AL.: "Template-Directed DNA Photoligation via a-5-Cyanovinyldeoxyuridine", ORGANIC LETTERS, vol. 7, no. 14, 2005, pages 2853 - 2856
"85th Annual Meeting on Chemical Society of Japan in Spring (2005) Koen Yokoshu II", 2005, article MASAYUKI OGINO ET AL.: "3' Mattangawa kara no a-5-cyanovinyldeoxy-uridine o Mochiita DNA Kagyakuteki Hikari Renketsu Hanno", pages: 1369
"79th Annual Meeting on Chemical Society of Japan in Spring (2001) Koen Yokoshu II", 2001, article KENZO FUJIMOTO: "Hikari o Mochiita Idenshi Sosaho (9) Hikari Renketsusei Shushoku Enki no Kosoteki Donyu", pages: 972
DMITRY G. SEMIZAROV ET AL.: "Stereoisomers of Deoxynucleoside 5'-Triphosphates as Substrates for Template-dependent and -independent DNA Polymerases", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 272, no. 14, 1997, pages 9556 - 9560
"89th Annual Meeting on Chemical Society of Japan in Spring (2009) Koen Yokoshu I", 13 March 2009, article YUKARI NITTA ET AL.: "Hikari Otosei a-Dideoxyuridine Yudotai o Donyu shita Cloning Vector no Kochiku", pages: 632
Attorney, Agent or Firm:
SAEKI, Norio et al. (Aminosan Kaikan Building 15-8, Nihonbashi 3-chome, Chuo-k, Tokyo 27, JP)
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