Title:
LINEAR LIPOPEPTIDE WITH END GROUP HAVING LIPOPHILIC STRUCTURE, PREPARATION METHOD FOR THE LOPOPEPTIDE, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2015/096725
Kind Code:
A1
Abstract:
Provided are a linear lipopeptide with an end group having a lipophilic structure, a preparation method for the lipopeptide, and a use thereof in preparing an anti-radiation injury medicament. The lipopeptide is one lipophilic structural unit and one linear polypeptide chain connected via an amide bond, where the lipophilic structural unit is located at either the N-terminus or the C-terminus of the linear polypeptide chain. The lipopeptide provides significant radiation injury protection activity.
Inventors:
LIU KELIANG (CN)
HAN HAN (CN)
GE CHANGHUI (CN)
ZHOU NING (CN)
XU XIAOYU (CN)
MENG QINGBIN (CN)
SUN FANGFANG (CN)
WANG WENLONG (CN)
TIAN YANG (CN)
HAN HAN (CN)
GE CHANGHUI (CN)
ZHOU NING (CN)
XU XIAOYU (CN)
MENG QINGBIN (CN)
SUN FANGFANG (CN)
WANG WENLONG (CN)
TIAN YANG (CN)
Application Number:
PCT/CN2014/094766
Publication Date:
July 02, 2015
Filing Date:
December 24, 2014
Export Citation:
Assignee:
INST PHARM & TOXICOLOGY AMMS (CN)
INST RADIATION MED AMMS PLA (CN)
INST RADIATION MED AMMS PLA (CN)
International Classes:
C07K7/06; A61K38/07; A61K38/08; A61P17/16; A61P37/02; A61P37/04; A61P39/00; C07K5/11
Foreign References:
| CN101631850A | 2010-01-20 |
Other References:
WANG, WENLONG.: "Anti-radiation Drug Screening from Structural Anologue of Lipopeptide H6101and Mechanism Research Chinese Master's Dissertations Full-text Database", MEDICINE AND HEALTH SCIENCES, 15 March 2014 (2014-03-15)
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
中国国际贸易促进委员会专利商标事务所 (CN)
中国国际贸易促进委员会专利商标事务所 (CN)
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