Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
LINOLENIC ACID-DERIVED CERAMIDE, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/093625
Kind Code:
A1
Abstract:
The present invention relates to the technical field of biomedicine. Disclosed is a linolenic acid-derived ceramide, which has a structure of general formula I or an isomer of general formula I: (I), wherein R1 is selected from (II) or (III), and R2 is selected from one of the following structures: (IV). Also disclosed are a preparation method and a use. In the present invention, long-chain linolenic acid reacts with sphingosine and phytosphingosine to obtain a class of structurally novel ceramide compounds; this class of compounds has a significant inhibitory effect on tyrosinase, can effectively prevent the production of melanin to achieve a good skin whitening effect, and can be used in the fields of cosmetics and the like.

Inventors:
YANG CHAOWEN (CN)
YE LIU (CN)
Application Number:
PCT/CN2023/123728
Publication Date:
May 10, 2024
Filing Date:
October 10, 2023
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
SHENZHEN DIKEMAN BIOTECHNOLOGY CO LTD (CN)
International Classes:
C07C233/20; A23L33/10; A23L33/12; A61K8/68; A61P17/00; A61P17/02; A61P17/18; A61P29/00; A61Q19/02; A61Q19/08; C07C231/02
Domestic Patent References:
WO2021252290A22021-12-16
Foreign References:
CN115894278A2023-04-04
CN115304509A2022-11-08
EP0097059A21983-12-28
US20080090913A12008-04-17
CN114436884A2022-05-06
US5631356A1997-05-20
KR20170100906A2017-09-05
Download PDF: