Title:
LIPID COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2022/054955
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a lipid composition which enables excellent nucleic acid delivery. Through the present invention, there is provided a lipid composition which includes a lipid represented by formula (1) or a salt thereof, a nucleic acid, at least one non-cationic lipid, and a lipid represented by the formula R51-L-(OCH2CH2)n-O-R52 (in the formula, R51 represents a C6-30 hydrocarbon group, L represents -CO- or a single bond, R52 represents a hydrogen atom or a C1-6 alkyl group, and n represents an integer of 10-150). In the formula, the symbols are as defined in the specification.
Inventors:
YAMADA NAOKI (JP)
KANEUMI SHUN (JP)
SUZUKI KEIKO (JP)
KASAGI NORIYUKI (JP)
NAKAMURA NAOTO (JP)
KANEUMI SHUN (JP)
SUZUKI KEIKO (JP)
KASAGI NORIYUKI (JP)
NAKAMURA NAOTO (JP)
Application Number:
PCT/JP2021/033635
Publication Date:
March 17, 2022
Filing Date:
September 14, 2021
Export Citation:
Assignee:
FUJIFILM CORP (JP)
International Classes:
A61K31/7088; A61K47/10; A61K47/18; A61K47/24; A61K47/28; A61K48/00; A61P25/00; A61P43/00; C12N15/88
Domestic Patent References:
| WO2019235635A1 | 2019-12-12 | |||
| WO2006080452A1 | 2006-08-03 | |||
| WO2010054401A1 | 2010-05-14 | |||
| WO2010144740A1 | 2010-12-16 | |||
| WO2010054405A1 | 2010-05-14 | |||
| WO2015095340A1 | 2015-06-25 | |||
| WO2009127060A1 | 2009-10-22 | |||
| WO2019235635A1 | 2019-12-12 |
Foreign References:
| JP2006290894A | 2006-10-26 | |||
| JP2006321800A | 2006-11-30 | |||
| US20130245107A1 | 2013-09-19 | |||
| JP2019504002A | 2019-02-14 | |||
| JP5288254B2 | 2013-09-11 |
Other References:
See also references of EP 4212162A4
Attorney, Agent or Firm:
SIKS & CO. (JP)
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