Title:
LIPID COMPOUND CONTAINING DISULFIDE BOND AND COMPOSITION THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/216232
Kind Code:
A1
Abstract:
Provided are a lipid compound and a composition thereof. The lipid compound comprises: a lipid compound represented by general formula (I) and/or (II), or a pharmaceutically acceptable salt of the lipid compound, or a solvate of the lipid compound, or a lipid nanoparticle formed by the lipid compound. The lipid compound is non-toxic, and the lipid nanoparticle formed by the lipid compound can efficiently deliver nucleic acids with high encapsulation efficiency and stability.
Inventors:
ZENG CHEN (CN)
SHEN ZHIGAO (CN)
WANG ZIQIAN (CN)
WANG PENG GEORGE (CN)
SHEN ZHIGAO (CN)
WANG ZIQIAN (CN)
WANG PENG GEORGE (CN)
Application Number:
PCT/CN2022/092697
Publication Date:
November 16, 2023
Filing Date:
May 13, 2022
Export Citation:
Assignee:
UNIV SOUTHERN SCI & TECH (CN)
International Classes:
C07C323/50; A61K9/127; C12N15/11
Domestic Patent References:
| WO2010054406A1 | 2010-05-14 | |||
| WO2020061457A1 | 2020-03-26 | |||
| WO2020219941A1 | 2020-10-29 | |||
| WO2011141705A1 | 2011-11-17 |
Foreign References:
| CN114213295A | 2022-03-22 |
Attorney, Agent or Firm:
DHC IP ATTORNEYS (CN)
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