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Title:
LIPID DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/1985/004398
Kind Code:
A1
Abstract:
Novel compounds of formula (I), wherein R1 represents C10-30 alkyl or alkylcarbonyl, R2 represents hydrogen, hydroxy, alkoxy, aralkyloxy, acyloxy, acylamino or a group represented by formula (II), (wherein W represents oxygen or sulfur, and R4 and R5 each represents hydrogen or alkyl or, when taken together, R4 and R5 form a ring together with the adjacent nitrogen atom), R3 represents an alkylene chain, one of X and Y represents an oxygen or sulfur atom and the other represents an optionally substituted imino group, and Z represents an optionally substituted amino group or ammonio group optionally forming a ring, and salts thereof show the effect of depressing PAF and are useful for prophylaxis and treatment of various circulatory troubles and allergic diseases and useful as oncostatic agents.

Inventors:
NOMURA HIROAKI (JP)
NISHIKAWA KOHEI (JP)
TSUSHIMA SUSUMU (JP)
Application Number:
PCT/JP1984/000163
Publication Date:
October 10, 1985
Filing Date:
April 03, 1984
Export Citation:
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Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD (JP)
International Classes:
C07C271/06; C07C275/50; C07C275/60; C07D207/09; C07D209/48; C07D211/56; C07D213/40; C07D213/75; C07D233/72; C07D239/54; C07D277/22; C07D277/28; C07D295/088; C07D295/13; C07D295/205; C07D295/215; C07D401/06; C07D401/12; C07D405/12; C07D417/06; C07D417/12; C07D521/00; (IPC1-7): C07C125/06; C07C155/02
Foreign References:
JPS5931738A1984-02-20
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