Title:
LIPID DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/1986/002349
Kind Code:
A1
Abstract:
Lipid derivatives represented by formula (I), (wherein R1 represents alkyl or alkylcarbamoyl, R2 represents H, optionally substituted hydroxy, optionally substituted amino or cyclic amino, R3 represents alkylene, R4 represents H, alkyl or aralkyl, X and Y each represents O, S or optionally substituted imino and, when Y represents imino, Y may form a ring together with the imino group represented by X or with R4, and Z represents an optionally substituted imino or nitrogen-containing heterocyclic ring) and salts thereof have a PAF-controlling effect, thus being useful as agents for prophylaxis and treatment of various circulatory organ troubles and allergic disorder and as antineoplastic agents.
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Inventors:
NOMURA HIROAKI (JP)
NISHIKAWA KOHEI (JP)
TSUSHIMA SUSUMU (JP)
NISHIKAWA KOHEI (JP)
TSUSHIMA SUSUMU (JP)
Application Number:
PCT/JP1984/000476
Publication Date:
April 24, 1986
Filing Date:
October 11, 1984
Export Citation:
Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD (JP)
International Classes:
C07C271/06; C07C275/50; C07C275/60; C07C329/00; C07C329/14; C07D207/09; C07D209/48; C07D211/56; C07D213/40; C07D213/75; C07D233/72; C07D239/54; C07D277/22; C07D277/28; C07D295/088; C07D295/13; C07D295/205; C07D295/215; C07D309/00; C07D401/06; C07D401/12; C07D405/12; C07D417/06; C07D417/12; C07D521/00; (IPC1-7): C07C93/16; C07C125/065; C07C125/073; C07C125/077; C07C154/00; C07C155/02; C07D207/09; C07D209/48; C07D213/40; C07D233/72; C07D239/55; C07D277/28; C07D295/08; C07D295/12; C07D295/20; C07D401/12; C07D405/12; C07D417/12
Foreign References:
| JPS5931738A | 1984-02-20 | |||
| JPS5988447A | 1984-05-22 | |||
| JPS59110663A | 1984-06-26 | |||
| JPS59112961A | 1984-06-29 |
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