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Title:
LIPID STRUCTURES AND COMPOSITIONS COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO/2023/250197
Kind Code:
A3
Abstract:
The disclosure relates to ionizable lipids and compositions comprising the ionizable lipids. Lipid-nanoparticle compositions comprised of an ionizable lipid, optionally in combination with other lipid components such as helper lipids, stabilization lipids and structural lipids, and a therapeutic agent, such as a nucleic acid, for delivery to mammalian cells or organs are described.

Inventors:
JUMAA MOUHANNAD (US)
KAMAL ZEESHAN (US)
BARMAN DIPTI (US)
Application Number:
PCT/US2023/026160
Publication Date:
February 22, 2024
Filing Date:
June 23, 2023
Export Citation:
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Assignee:
TURN BIOTECHNOLOGIES INC (US)
International Classes:
C07C219/06; A61K9/00; C07C229/12; C07C229/22; C07C233/20; C07D205/04; C07D207/08; C07D207/16; C07D207/327; C07D295/15; C12N15/00
Domestic Patent References:
WO2020219876A12020-10-29
Foreign References:
EP3750867A12020-12-16
EP3083556B12019-12-25
EP3835287A12021-06-16
US20200331841A12020-10-22
US20210169804A12021-06-10
Attorney, Agent or Firm:
MOHR, Judy M. et al. (US)
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