Title:
LIPOSOME PHARMACEUTICAL COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/067849
Kind Code:
A1
Abstract:
Provided are a liposome and a composition thereof. When the liposome and the composition thereof serve as a medicament carrier, by means of specific drug-loading conditions and processes, 1) a high drug-loading capacity (with the highest drug-loading capacity not lower than 18%) is obtained; and 2) the encapsulation efficiency is not less than 85% when the drug-loading capacity is lower than the highest drug-loading capacity (18%). A medicament liposome-treprostinil liposome combination prepared from said liposome has a good therapeutic effect on the treatment of peripheral arterial occlusive disease or pulmonary arterial hypertension.
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Inventors:
YAO MENG (CN)
SHI XIAOQING (CN)
LIN YIFONG (CN)
SHI XIAOQING (CN)
LIN YIFONG (CN)
Application Number:
PCT/CN2023/122824
Publication Date:
April 04, 2024
Filing Date:
September 28, 2023
Export Citation:
Assignee:
SHANGHAI JEMINCARE PHARMACEUTICAL CO LTD (CN)
International Classes:
A61K9/127; A61K31/5575; A61K31/5585; A61P11/00
Foreign References:
| CN111372580A | 2020-07-03 | |||
| CN101795671A | 2010-08-04 | |||
| CN112384224A | 2021-02-19 | |||
| CN113811307A | 2021-12-17 | |||
| US5939096A | 1999-08-17 | |||
| CN1717221A | 2006-01-04 | |||
| CN106999419A | 2017-08-01 | |||
| CN112004527A | 2020-11-27 |
Attorney, Agent or Firm:
BEIJING ORIGINTELLIGENCE IP LAW FIRM (CN)
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