INTERNATIONAL SEARCH REPORT PCT/US00/09657 C. (Continuation) DOCUMENTS CONSIDERED TO BE RELEVANT Category Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No. A WO 94 05777 A (HOPE CITY; NADLER JERRY L 1-6 (US) ; NATARAJAN RAMA DEVI (US); GU JIALI) 17 March 1994 (1994-03-17) the whole document A ROUZER C A ET AL:"CHARACTERIZATION OF 1-6 CLONED HUMAN LEUKOCYTE 5 LIPOXYGENASE EXPRESSED IN MAMMALIAN CELLS" JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 263, no. 21,1988, pages 10135-10140, XP002143912 ISSN:0021-9258 the whole document A BOADO R. ET AL. :"Differential expression 1-6 of arachidonate 5-lipoxygenase transcripts in human brain tumors: evidence for the expression of a multitranscript family" PNAS U. S. A., vol. 89, 1992, pages 9044-9048, XP002143913 the whole document 1 h rational application No. PCT/US 00/09657 INTERNATIONAL SEARCH REPORT Box I Observations where certain claims were found unsearchable (Continuation of item 1 of first sheet) This international Search Report has not been established in respect of certain claims under Article 17 (2) (a) for the following reasons: 1. Claims Nos. : because they relate to subject matter not required to be searched by this Authority, namely: 2. Claims Nos.: because they relate to parts of the International Application that do not comply with the prescribed requirements to such an extent that no meaningful International Search can be carried out, specifically: 3. j Claims Nos.: because they are dependent claims and are not drafted in accordance with the second and third sentences of Rule 6.4 (a). Box 11 Observations where unity of invention is lacking (Continuation of item 2 of first sheet) This international Searching Authority found multiple inventions in this international application, as follows: see additional sheet 1. As all required additional search fees were timely paid by the applicant, this International Search Report covers all searchable claims 2. As all searchable claims could be searched without effort justifying an additional fee, this Authority did not invite payment of any additional fee. 3. As only some of the required additional search fees were timely paid by the applicant, this International Search Report covers only those claims for which fees were paid, specifically claims Nos.: 4. No required additional search fees were timely paid by the applicant. Consequently, this International Search Report is restricted to the invention first mentioned in the claims ; it is covered by claims Nos.: Claims 1-6 partially. Remark on Protest The additional search fees were accompanied by the applicant's protest. u No protest accompanied the payment of additional search fees. u International Application No. PCT/US 00/09657 FURTHER INFORMATION CONTINUED FROM PCT/ISA/210 This International Searching Authority found multiple (groups of) inventions in this international application, as follows: 1. Claims: 1-6 partially An isolated polynucleotide selected from: a polynucleotide comprising SEQ ID NO : 1, encoding a polypeptide comprising SEQ ID NO : 2, and a polynucleotide hybridizing thereto under high stringent conditions. An isolated oligonucleotide comprising from about 16 to about 40 bases of said polynucleotide. An isolated polypeptide selected from: a polypeptide comprising SEQ ID NO : 2, and a polypeptide encoded by said polynucleotide. An antibody specific for said polypeptide. A cell and a transgenic mouse engineered to contain said polynucleotide. 2. Claims: 1-6 partially idem for SEQ ID NO : 3,4 3. Claims: 1-6 partially idem for SEQ ID NO : 5,6 4. Claims: 1-6 partially idem for SEQ ID NO : 7,8 5. Claims: 1-6 partially idem for SEQ ID NO : 9,10 6. Claims: 1-6 partially idem for SEQ ID NO : 11,12 7. Claims: 1-6 partially idem for SEQ ID NO : 13,14 8. Claims: 1-6 partially idem for SEQ ID NO : 15,16 9. Claims: 1-6 partially Intemational Application No. PCT/US 00/09657 FURTHER INFORMATION CONTINUED FROM PCT/ISA/210 idem for SEQ ID NO : 17,18 10. Claims: 1-6 partially idem for SEQ ID NO : 19,20 11. Claims: 1-6 partially idem for SEQ ID NO : 21,22 12. Claims: 1-6 partially idem for SEQ ID NO : 23,24 13. Claims: 1-6 partially idem for SEQ ID NO : 25,26 14. Claims: 1-6 partially idem for SEQ ID NO : 27,28 15. Claims: 1,2,5,6 An isolated polynucleotide selected from: a polynucleotide comprising SEQ ID NO : 29, and a polynucleotide hybridizing thereto under high stringent conditions. An isolated oligonucleotide comprising from about 16 to about 40 bases of said polynucleotide. A cell and a transgenic mouse engineered to contain said polynucleotide. INTERNATIONAL SEARCH REPORT tnterrnai Apptication No rmation on patent tamily members PC I/J S () (i 9 657 Patent document Publication Patent family Publication cited in search report date member (s) date WO 9913111 A 18-03-1999 EP 1012343 A 28-06-2000 EP 0325773 A 02-08-1989 JP 2000453 A 05-01-1990 WO 9405777 A 17-03-1994 AU 674339 B 19-12-1996 AU 4840393 A 29-03-1994 CA 2077461 A C1-03-1994 EP 0621895 A 02-11-1994 EP 0696193 A 14-02-1996 JP 75û0254 T 12-C1-1995 WO 9518609 A 13-07-1995