Title:
LUMINAL STRUCTURE, AND METHOD FOR MANUFACTURING LUMINAL STRUCTURE
Document Type and Number:
WIPO Patent Application WO/2024/071433
Kind Code:
A1
Abstract:
[Problem] To provide a method for manufacturing a luminal structure having an appropriate structure by three-dimensionally adjusting the unevenness inside the luminal structure. [Solution] A method for manufacturing a luminal structure, the method including: an in-mold temporary fixing agent acquisition step for acquiring an in-mold temporary fixing agent, the temporary fixing agent being housed in a mold which has a recess corresponding to the outer shape of the luminal structure, and the temporary fixing agent having a core-forming member corresponding to the luminal body part of the luminal structure inserted thereinto; and an in-mold temporary fixing agent solidification step for solidifying the in-mold temporary fixing agent while generating bubbles inside the in-mold temporary fixing agent with the use of the core-forming member.
Inventors:
ONOE HIROAKI (JP)
TANAKA SHUMA (JP)
ITAI SHUN (JP)
TOYOHARA TAKAFUMI (JP)
TANAKA SHUMA (JP)
ITAI SHUN (JP)
TOYOHARA TAKAFUMI (JP)
Application Number:
PCT/JP2023/035893
Publication Date:
April 04, 2024
Filing Date:
October 02, 2023
Export Citation:
Assignee:
UNIV KEIO (JP)
UNIV TOHOKU (JP)
UNIV TOHOKU (JP)
International Classes:
C12M3/00; C12N5/071
Domestic Patent References:
| WO2020208094A1 | 2020-10-15 |
Other References:
TANAKA SHUMA; ITAI SHUN; ONOE HIROAKI: "A Three-Dimensional Artificial Intestinal Tissue With A Crypt-Like Inner Surface", 2023 IEEE 36TH INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS), IEEE, 15 January 2023 (2023-01-15), pages 456 - 459, XP034301989, DOI: 10.1109/MEMS49605.2023.10052541
NIKOLAEV MIKHAIL; MITROFANOVA OLGA; BROGUIERE NICOLAS; GERALDO SARA; DUTTA DEVANJALI; TABATA YOJI; ELCI BILGE; BRANDENBERG NATHALI: "Homeostatic mini-intestines through scaffold-guided organoid morphogenesis", NATURE, vol. 585, no. 7826, 16 September 2020 (2020-09-16), pages 574 - 578, XP037254028, DOI: 10.1038/s41586-020-2724-8
KUN YAN: "Wire templated electrodeposition of vessel-like structured chitosan hydrogel by using a pulsed electrical signal", SOFT MATTER, ROYAL SOCIETY OF CHEMISTRY, GB, vol. 16, no. 41, 28 October 2020 (2020-10-28), GB , pages 9471 - 9478, XP093153440, ISSN: 1744-683X, DOI: 10.1039/D0SM01134G
NIKOLAEV MIKHAIL; MITROFANOVA OLGA; BROGUIERE NICOLAS; GERALDO SARA; DUTTA DEVANJALI; TABATA YOJI; ELCI BILGE; BRANDENBERG NATHALI: "Homeostatic mini-intestines through scaffold-guided organoid morphogenesis", NATURE, vol. 585, no. 7826, 16 September 2020 (2020-09-16), pages 574 - 578, XP037254028, DOI: 10.1038/s41586-020-2724-8
KUN YAN: "Wire templated electrodeposition of vessel-like structured chitosan hydrogel by using a pulsed electrical signal", SOFT MATTER, ROYAL SOCIETY OF CHEMISTRY, GB, vol. 16, no. 41, 28 October 2020 (2020-10-28), GB , pages 9471 - 9478, XP093153440, ISSN: 1744-683X, DOI: 10.1039/D0SM01134G
Attorney, Agent or Firm:
HIROSE Takayuki (JP)
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