Title:
LYOPHILIZATION PRODUCT
Document Type and Number:
WIPO Patent Application WO/2003/094889
Kind Code:
A1
Abstract:
An aqueous solution with a pH value of higher than 2 but not higher than 4, comprising a substituted or unsubstituted amidino group having physiologically active substance; a lyophilization product obtained by lyophilizing the aqueous solution; an injection comprising the aqueous solution or the lyophilization product; and an injection kit.
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Inventors:
FUJII YOSHIMINE (JP)
SUZUKI NORIO (JP)
SUZUKI NORIO (JP)
Application Number:
PCT/JP2003/005940
Publication Date:
November 20, 2003
Filing Date:
May 13, 2003
Export Citation:
Assignee:
DAIICHI SEIYAKU CO (JP)
FUJII YOSHIMINE (JP)
SUZUKI NORIO (JP)
FUJII YOSHIMINE (JP)
SUZUKI NORIO (JP)
International Classes:
A61K9/19; A61K9/20; A61K31/40; A61K31/404; A61K31/445; (IPC1-7): A61K9/08; A61K9/19; A61K31/40; A61K31/404; A61K31/445
Domestic Patent References:
WO2000064442A1 | 2000-11-02 | |||
WO1999036096A1 | 1999-07-22 | |||
WO2002041892A1 | 2002-05-30 | |||
WO2002060873A1 | 2002-08-08 |
Foreign References:
US4853416A | 1989-08-01 | |||
JPS58103312A | 1983-06-20 | |||
EP0750913A2 | 1997-01-02 |
Other References:
KAWAI Y. ET AL.: "Photodecarboxylation of DX-9065a, a new factor Xa inhibitor, in aqueous solution", CHEM. PHARM. BULL., vol. 46, no. 1, 1998, pages 131 - 135, XP002971354
Attorney, Agent or Firm:
The, Patent Corporate Body Aruga Patent Office (3-6 NIHONBASHININGYOCHO 1-CHOM, CHUO-KU Tokyo, JP)
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