Title:
MACROCYCLIC AND CAGE-LIKE MOLECULES BASED ON BIPHENYLARENE AND DERIVATIVE COMPOUNDS, SYNTHESIS METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/073456
Kind Code:
A1
Abstract:
Provided are a class of macrocyclic and cage-like molecules based on a biphenylarene and derivative compounds, a synthesis method therefor and the use thereof. A series of new macrocycles and molecular cages are obtained in a high yield from a bis-(2,4-dialkoxyphenyl)arene (naphthalene, anthracene, pyrene, porphyrin, etc.) or a tri-(2,4-dialkoxyphenyl)arene (benzene, sym-tribenzobenzene) and paraformaldehyde under the catalysis of a Lewis acid. In addition, perhydroxybiphenylarenes (tetrabiphenyl trimer, naphthalene dimer, etc.) can be obtained by means of demethylation, and a variety of water-soluble derivatives can be obtained by further modification, with same exhibiting a good bond ability for guest molecules (purpurine, etc.). Moreover, the functional group introduced into the backbone enables the macrocycle to have excellent adsorption and separation capabilities and a photophysical property. The macrocyclic and cage-like molecules have commercially available raw materials, are simple to synthesize, have a high yield, and are convenient to modify, such that same have wide application prospects in gas adsorption and separation, facilitate performance improvement of luminescent materials, perform adsorption of water-soluble toxic substances, etc.
Inventors:
LI CHUNJU (CN)
XU KAIDI (CN)
ZHANG ZHIYUAN (CN)
XU KAIDI (CN)
ZHANG ZHIYUAN (CN)
Application Number:
PCT/CN2020/120189
Publication Date:
April 22, 2021
Filing Date:
October 10, 2020
Export Citation:
Assignee:
UNIV TIANJIN (CN)
International Classes:
C07C41/30; B01D15/08; B01J20/22; B01J20/30; C07C43/20; C07C43/205; C07C43/215; C07C45/75; C07C46/00; C07C49/755; C07C49/84; C07C50/34; C07C51/367; C07C59/125; C07D471/08; C07D487/18; C07D487/22; C07D513/18; C07F5/02; C09K11/06; G01N21/64; G01N24/08; G01N25/48
Foreign References:
| CN110642684A | 2020-01-03 | |||
| CN105884585A | 2016-08-24 | |||
| CN106188560A | 2016-12-07 |
Other References:
XU KAIDI, ZHANG ZHI‐YUAN, YU CHENGMAO, WANG BIN, DONG MING, ZENG XIANQIANG, GOU RUI, CUI LEI, LI CHUNJU: "A Modular Synthetic Strategy for Functional Macrocycles", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, VERLAG CHEMIE, vol. 59, no. 18, 27 April 2020 (2020-04-27), pages 7214 - 7218, XP055803040, ISSN: 1433-7851, DOI: 10.1002/anie.202000909
VILA CARLOS, CEMBELLÍN SARA, HORNILLOS VALENTÍN, GIANNERINI MASSIMO, FAÑANÁS-MASTRAL MARTÍN, FERINGA BEN L.: "t BuLi-Mediated One-Pot Direct Highly Selective Cross-Coupling of Two Distinct Aryl Bromides", CHEMISTRY - A EUROPEAN JOURNAL, JOHN WILEY & SONS, INC, vol. 21, no. 44, 26 October 2015 (2015-10-26), pages 15520 - 15524, XP055803044, ISSN: 0947-6539, DOI: 10.1002/chem.201502709
VILA CARLOS, CEMBELLÍN SARA, HORNILLOS VALENTÍN, GIANNERINI MASSIMO, FAÑANÁS-MASTRAL MARTÍN, FERINGA BEN L.: "t BuLi-Mediated One-Pot Direct Highly Selective Cross-Coupling of Two Distinct Aryl Bromides", CHEMISTRY - A EUROPEAN JOURNAL, JOHN WILEY & SONS, INC, vol. 21, no. 44, 26 October 2015 (2015-10-26), pages 15520 - 15524, XP055803044, ISSN: 0947-6539, DOI: 10.1002/chem.201502709
Attorney, Agent or Firm:
BEIJING ORIGINTELLIGENCE IP LAW FIRM (CN)
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