Title:
MACROCYCLIC COMPOUND CONTAINING BENZOHETEROCYCLE AND ACTING AS EGFR KINASE INHIBITOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/166741
Kind Code:
A1
Abstract:
A macrocyclic compound containing a benzoheterocycle and acting as an EGFR kinase inhibitor. Specifically disclosed is a compound as represented by formula I or a pharmaceutically acceptable salt, a stereoisomer and a tautomer thereof, a preparation method therefor, a pharmaceutical composition containing the compound, and the medical use thereof.
Inventors:
LIU FEI (CN)
PENG YAN (CN)
XU HONGJIANG (CN)
REN CHENG (CN)
YAN ZHENGLEI (CN)
PENG YAN (CN)
XU HONGJIANG (CN)
REN CHENG (CN)
YAN ZHENGLEI (CN)
Application Number:
PCT/CN2022/074255
Publication Date:
August 11, 2022
Filing Date:
January 27, 2022
Export Citation:
Assignee:
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN)
International Classes:
A61K31/439; A61P35/00; C07D487/22; C07D498/22
Domestic Patent References:
| WO2020260252A1 | 2020-12-30 | |||
| WO2001051456A2 | 2001-07-19 | |||
| WO2007129183A2 | 2007-11-15 | |||
| WO2002076438A2 | 2002-10-03 | |||
| WO2020132582A1 | 2020-06-25 | |||
| WO2010029300A1 | 2010-03-18 |
Foreign References:
| CN111741954A | 2020-10-02 |
Attorney, Agent or Firm:
INSIGHT INTELLECTUAL PROPERTY LIMITED (CN)
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