OF A TISSUE

CROSS REFERENCE TO RELATED APPLICATIONS

The present application claims priority to co-pending US Patent Application Serial No. 12/628,990 filed on December 01, 2009, entitled "Magnetic System for Treatment of Cellular Dysfunction of a Tissue or an Extracellular Matrix Disruption of a Tissue". This application is incorporated in its entirety.

FIELD

[0002] The present embodiments generally relate to a system for therapeutically treating afflicted tissue with magnetic fields that can be worn by a human or an animal such as a dog, a cat, a horse, or another animal.

BACKGROUND

[0003] A need exists for an inexpensive portable system for therapeutic treatment of tissue disease of humans and animals that is non-invasive, easy to apply, and quick to provide relief.

[0004] The present embodiments meet these needs.

BRIEF DESCRIPTION OF THE DRAWINGS

[0005] The detailed description will be better understood in conjunction with the accompanying drawings as follows:

[0006] Figure 1 is a diagram of bipolar square-wave pulses produced with a pulse generator.

[0007] Figure 2 is a diagram showing a pulse blast. Figure 3 is a diagram of the pulse generator.

Figure 4 is a detailed view of two of the electromagnetic coils usable in the system.

Figure 5 is a detailed view of an arrangement of electromagnetic coils around a limb.

Figure 6 is a diagram showing a processor in communication with an administrative server.

Figure 7 is diagram of a magnetic array applied over a limb.

Figure 8A is an animal wearing a kit embodiment of the system.

Figure 8B shows the opposite side of the animal shown in Figure 8A.

Figure 9 is a view of a pet bed embodiment of the system.

The present embodiments are detailed below with reference to the listed Figures.

DETAILED DESCRIPTION OF THE EMBODIMENTS

Before explaining the present system and apparatus in detail, it is to be understood that the system and apparatus are not limited to the particular embodiments and that the embodiments can be practiced or carried out in various ways.

The present embodiments relate to a system and apparatus used for treating various ailments. The embodiments can treat injury to the musculoskeletal system, osteoarthritis, and other conditions that result in pain, including pain of the joints, bones, and tissues of the musculoskeletal system using a system, a pet bed, and a kit.

Various terms are used herein with particular meanings.

The term "pulse blast", as used herein, refers to pulse blasts that can have from about 1 pulse to about 100 pulses contained within the pulse blast. Pulse blasts can be formed using pulses that are not sine -waves, but are square-waves of electrical power delivered to electromagnetic coils, resulting in an induced magnetic pulse that penetrates tissue that is disposed between or near the electromagnetic coils.

[00021] The term "pulse", as used herein, refers individual pulses that are created and contained within each pulse blast. Multiple pulses can be used to form a pulse blast.

[00022] The term "power supply", as used herein, refers to the use of batteries, line power from a wall outlet transformed into DC power at a suitable voltage, or other suitable sources of electrical energy.

[00023] The term "bi-directional communication and power port" refers to connectors such as a D-subminiature 9-pin connector, stereo audio cable connectors, or other suitable electronic connectors.

[00024] The term "communication signal" refers to signals used to drive a voltage multiplier, to energize at least two magnetic coils, or to provide a signal to reprogram a microcontroller.

[00025] The term "microcontroller" refers to any suitable low voltage microcontroller that is commercially available.

[00026] The term "low voltage" refers to a voltage from about 1 volt to about 25 volts. In an embodiment, a 9-volt battery can be used to power the microcontroller that provides the electromagnetic pulse bursts through at least one pair of wires to the electromagnetic coils which can be used in a stacked arrangement, a "figure 8" arrangement, a sandwich arrangement with the tissue for therapy treatment located between the coils or a side by side parallel arrangement.

[00027] The term "low amperage" refers to amperages of less than 1 amp and greater than

0.001 amps, during the generation of stimulation pulses where amperage is averaged over a period of at least 10 seconds.

[00028] The term "low power" refers to the product of one of the voltages from the range of low voltages with one of the amperages from the range of low amperages. [00029] The term "processor" refers to a component within a microcontroller that makes computations and decisions and is capable of determining precise values of time and logic states for driving elements of the pulse generator, and is capable of comparing a first set of signals to predetermined values stored in an associated data storage in communication with the processor.

[00030] The term "data storage" refers to a flash memory, a removable jump drive, a hard drive, or a portion of the microcontroller that is either within or outside of the microcontroller that allows software, firmware, and data to be stored, recalled, modified, and executed therefrom.

[00031] The term "computer instructions with preset pulse parameters" refers to computer instructions that define an exact nature of the pulse blasts to be delivered from a pulse generator.

[00032] As the term is used herein, "vectors" refers to a mathematical representation of a magnetic field which contains quantitative information about both the magnetic field direction and the field amplitude or strength.

[00033] The term "normal-to plane axis", as used herein, refers to an axis that is perpendicular to a plane surface of an individual coil or a coil array encapsulated within a flexible polymer. For example, if the magnetic coil is elliptical, the plane surface would be the plane of the first surface of the elliptical shaped magnetic coil.

[00034] The term "mechanically flexible polymer coating", as used herein, refers to a flexible, bendable, not brittle coating that can contain an elastomeric material such as silicone, urethane, or a thermoplastic elastomer compound. In embodiments, the mechanically flexible polymer coating can be a washable, heat resistant thin coating of a polymer such as a polypropylene homopolymer, a polypropylene copolymer, or a cross linked polymer of polypropylene and polyethylene, forming a bendable, impact resistant, coating such as coatings used to encapsulate electrical wires. The mechanical flexible polymer coating can be a laminate with a first coating covering a second coating that encapsulates the magnetic coils while allowing the magnetic coils to be flexed and bent into a desired shape.

The term "computer instructions in the data storage for instructing the processor to generate random pulse blasts, random pulses, or randomization of selected pulse parameters according to a random pulse generator, as the dosage amounts within the specified range of pulse parameters" refers to a series of algorithmic computer codes that can allow the pulse generator to sequentially generate pulses or pulse blasts with a predetermined number of pulses in the pulse blasts and having a predetermined time interval between the pulse blasts or pulses. In embodiments, a random number generator can be used to generate variable pulse blasts in the dosage amounts.

[00036] The phrase "saddlebag" refers to a single pouch or a configuration of two pouches connected together which can reside on a back of an animal. The saddle bag can have a first pouch riding on a first side of an animal connected to a second pouch riding on a second side of the animal, so as to allow for safe carriage of the power supply and the pulse generator by an animal. A support strap can wrap around the front or chest area of the animal enabling the two pouches to stay securely on the animal for therapeutic purposes.

[00037] As this term is used herein, the "magnetic Halbach array" can be an array of magnetic elements in a one-dimensional (linear) or a two-dimensional (planar) array wherein in-plane magnetic field generators reside in the magnetic Halbach array and can act to produce large amplitude magnetic fields on one side of the magnetic Halbach array, while producing a minimal magnetic field on the other side of the magnetic Halbach array.

[00038] The term "animal actuated on/off switch" refers to a simple mechanical pressure switch, an optical detector switch, a heat detector switch, a motion detector switch, a capacitance proximity detector switch, a sound or vibration detector switch, an ultrasonic detector switch, or similar means by which the presence of an animal can be established and detected by the microcontroller.

[00039] The term "heating element" refers to an electrical element that allows the generation of controlled heat which can be applied to pet bedding.

[00040] The term "cooling element" refers to an electrical element such as an array of Peltier devices, which allow heat to be removed from part or all of a pet bed or other animal bedding.

[00041] Embodiments can be used for treatment of a cellular dysfunction of tissue or an extracellular matrix disruption of a tissue, or both of these problems, and can use a pulse generator and at least one pair of magnetic coils.

[00042] Embodiments can also be used to accelerate healing of bone, skin, nerves, musculoskeletal systems, and cardiovascular systems.

[00043] Embodiments can be used to promote the healing of refractory or non-healing bone fractures; to reduce swelling from osteoarthritis or rheumatoid arthritis; to reduce scar tissue formation in skin, tendons, muscles and ligaments; to reduce infection rate; and to promote increased joint range of motion subsequent to injury or a degenerative disease.

[00044] Embodiments can be used to treat or reduce pain including idiopathic joint pain, pain associated with fibromyalgia, lower back pain, compartment pain, referred pain, acute pain, chronic pain, and migraines.

[00045] Embodiments can be used to treat strains of muscles, tendons, ligaments, bulging vertebral disks, osteopenia, temporomandibular joint, and craniofacial structures.

[00046] Embodiments can be used to treat critical defects in bone; injured cardiovascular tissues; heart failure; heart injury by reducing monocyte-induced swelling; spinal cord injury by promoting nerve re-growth, inhibiting fibroblast infiltration and growth, and inhibiting scar formation; nerve injury; nerve degeneration; loss of bladder or bowel control; neurogenic incontinence; neurogenic erectile dysfunction; ulcers; injury to the rotator cuff; internal organ disorders including liver, pancreas, kidney and lung disease; tremors associated with Parkinson's disease, ataxia, or multiple sclerosis; non-responsive wounds including diabetic foot ulcer and postsurgical abdominal ulcer; and to treat cancer by inhibiting tumor formation and growth.

[00047] Embodiments can be used to improve outcome and to accelerate healing after surgery or injury of the cornea including LASIK surgery and corneal transplants; engraftment of surgical implants; ejection fraction after surgery for heart failure; cardiac muscle regeneration; functional outcome after heart surgery as measured by the 6-minute walk test; blood flow in ischemic limbs; limb salvage after removal of blood flow; or strength of tissues following injury.

[00048] Embodiments can also be used to decrease cardiac scarring after heart failure or surgery; accelerate nerve regeneration; treat strokes by improving blood flow to the affected areas of the brain; reduce functional loss following a stroke; and recover tone of the muscles of the urogenital system.

[00049] Embodiments can be used as an adjunct to stem cell therapy to improve engraftment; for in vivo amplification of stem cells, to accelerate phenotypic development of the stem cells into the desired tissue phenotypes, for targeting engraftment, and for guiding phenotypic development into the desired tissue types.

[00050] The pulse generator can provide a signal to or excite at least one very low power electromagnetic coil pair in communication with the pulse generator. The very low power electromagnetic coil pair can generate a plurality of pulse blasts when the pulse generator sends the signal or excites the very low power electromagnetic coil pair. Each pulse blast can be formed from one or more pulses. The pulse generator can have at least one power supply such as two connected batteries or a battery and a battery charger. An electrical current can be generated by the power supply or the pulse generator. [00051] The pulse generator can have a bi-directional communication and power port for flowing power into and out of the pulse generator and flowing communication signals into and out of the pulse generator.

[00052] The pulse generator can have a microcontroller in communication with the bidirectional communication and power port.

[00053] The microcontroller can have a processor that can be in communication with the power supply. Data storage can be in communication with the processor and computer instructions with preset pulse parameters can be stored in the data storage.

[00054] A pair of first transistors can be in communication with the microcontroller. In embodiments, multiple pairs of first transistors can be in communication with the microcontroller.

[00055] The first pair of transistors can allow the microcontroller to control power flow into the voltage multiplier.

[00056] A voltage multiplier can be connected to the at least one pair of first transistors. The voltage multiplier can include one or more diodes and one or more capacitors. The voltage multiplier can include combinations of diodes and capacitors for communication with the microcontroller for increasing or decreasing the output voltage of the pulse generator.

[00057] In embodiments, the diodes can be rapid switching diodes, and the capacitors can be surface mount ceramic capacitors.

[00058] In embodiments, the voltage multiplier can be a Villard Cascade Voltage Multiplier, though other configurations may be employed.

[00059] The pulse generator can have a pair of second transistors in communication with the voltage multiplier to form an output stage. In embodiments, the pulse generator can have multiple second transistors. The second transistors can be controlled by the microcontroller to form or produce an electrical signal to send to a very low power electromagnetic coil pair to generate a plurality of pulse blasts or pulses.

[00060] In embodiments, the second transistors can allow a microcontroller to control electrical energy flow from the pulse generator to electromagnetic coils; thereby controlling pulse parameters.

[00061] Embodiments can further include a pair of power supply conduits, which can be wires that each connect to at least one pair of very low power electromagnetic coils. The pair of power supply conduits, such as those connecting the power supply to the pulse generator, or connecting the pulse generator to the coils, can be wires.

[00062] Embodiments can include at least one Helmholtz-like magnetic coil pair sized to generate a plurality of pulse blasts which can have a slew rate of at least 200 kiloGauss per second (kG/s).

[00063] Each very low power electromagnetic coil pair can have a first electromagnetic coil with a first electromagnetic coil diameter and a first electromagnetic coil axis. A first electromagnetic coil first side can have a first polarity, and a first electromagnetic coil second side can have a second polarity. The first electromagnetic coil can connect to one of the pair of power supply conduits.

[00064] The very low power electromagnetic coil pair can have a second electromagnetic coil with a second electromagnetic coil diameter and a second electromagnetic coil axis. A second electromagnetic coil first side can have a first polarity, and a second electromagnetic coil second side can have a second polarity. The second electromagnetic coil can connect to one of the power supply conduits.

[00065] The first electromagnetic coil can be disposed opposite the second electromagnetic coil, enabling a Helmholtz-like, very low power electromagnetic coil pair to treat tissue placed between or proximate the first electromagnetic coil and second electromagnetic coil and their associated pulse blasts. For the embodiment having Helmholtz-like electromagnetic coil pairs, the first electromagnetic coil and the second electromagnetic coil can be disposed at separations from about 0.1 radius to about 20 radii.

The first electromagnetic coil and second electromagnetic coil can be oriented so that when energized using the pulse generator, a plurality of magnetic square -wave pulses can be generated with slew rates of at least 200 kG/s for at least a duration about 0.1 microsecond to about 200 microseconds without forming a sine shaped pulse wave.

Each formed magnetic square-wave pulse can have a leading edge and a trailing edge. Each leading edge to trailing edge can have a duration of about 0.1 microsecond to about 200 microseconds. Each leading or trailing edge can maintain a slew rate of at least about 200 kG/s.

In embodiments, pulse parameters controlled by the microcontroller can include a pulse voltage, a pulse duration, a pulse polarity, a number of pulses per unit of time; a number of pulses per pulse blast, a time duration between pulses in each pulse blast, a time duration between pulse blasts, or combinations thereof.

In one or more embodiments, the pulse voltage can range from about 5 volts to about 200 volts. In embodiments, the pulses can be bipolar pulses.

[00071] In embodiments, an external power supply, such as a 110 volt wall outlet or a generator, can be connected to the power supply to allow for uninterrupted pulse blast generation for a dosage amount of time. The external power supply can also be a single battery or a plurality of connected batteries. The pulse generator can have an on/off switch for actuating the external power supply to supply power to the pulse generator.

[00072] The external power supply can be one or more DC batteries, such as four "C" batteries, two or more "AA" batteries, or one or more 9-volt batteries. The pulse generator can be run on 110 volts of power provided that there is a current conditioning device secured to the generator. In one or more embodiments, the pulse generator can run on 220 volts AC. For example, the pulse generator can be configured to be operated using common United States line voltage or common European line voltage.

[00073] In embodiments, from about t2 transistors to about 40 transistors can be utilized.

The capacitor and the first and second transistor pairs can be connected together in an H-bridge configuration.

[00074] The microcontroller can include computer instructions, such as a soft remote terminal unit instruction, allowing the microcontroller to be reconfigurable on-line, without any down time of the pulse generator. The pulse generators of an array of pulse generators can be reconfigured on-line using communication from an administrative server in communication with the pulse generators through a network which can be a wireless network.

[00075] Each pulse blasts can be composed of positive polarity pulses, negative polarity pulses, or combinations thereof. The pulse blasts can include different numerical quantities of pulses. Differing intervals of time can occur between pulse blasts

[00076] The alignment of the axis of each electromagnetic coil can range from being parallel and coaxial to being anti-parallel, adjacent, and coplanar. A plurality of the pairs of the very low power electromagnetic coils can be formed into a magnetic array with a common controller for treating a large area of tissue. The magnetic array can be formed to surround an entire limb.

[00077] The magnetic array can generate pulses in controlled sequences to produce a plurality of magnetic field vectors that rotate through a space proximate to the magnetic array over a preset unit of time and/or that translate through the space near the magnetic array over time.

[00078] The magnetic array can be a set of electromagnetic coils arranged in such a manner as to allow one common controller to energize or de-energize any combination of electromagnetic coils in the magnetic array; thereby allowing the common controller to control the resulting magnetic field within and near the magnetic array.

[00079] The common controller of the magnetic array can be a microcontroller, which controls the pulse generator to generate pulses or pulse blasts which can be communicated to a pair of magnetic coils or a magnetic coil array. The coils can be electromagnetic coils or magnetic coils.

[00080] The plurality of electromagnetic coils can be arranged into a member of the group consisting of: a two dimensional Halbach array, a one dimensional Halbach array, and combinations thereof.

[00081] At least one pair of very low power electromagnetic coils of each Halbach arrays can have an in-plane axis to act as a flux conduit between a normal-to-plane axis of at least one other pair of magnetic coils.

[00082] Each Halbach array can contain flux concentrators of iron, ferrite or similar magnetic material to concentrate the magnetic field at specified points within each Halbach array.

[00083] The distance between the pairs of electromagnetic coils in each Halbach array can be adjusted to range from about 0.5 inches to about 10 inches, measured as the center-to-center distance between the normal-to-plane axis.

[00084] Each Halbach array can be sealed within a mechanically flexible polymer coating, which allows for the generation of magnetic fields to be unimpeded. Each Halbach array can be mechanically flexible and conformable to adapt to a curvature of an anatomic surface of a head, a neck, a torso, a pelvis, a limb, or combinations thereof.

[00085] In embodiments, additional computer instructions can be in the data storage of the pulse generator for instructing the processor to generate, at random intervals, pulse blasts or pulses as the dosage amounts within the specified range of pulse parameters. Pulses with a duration longer than about 200 microseconds can be used to produce unipolar magnetic pulses. [00086] The pair of very low power electromagnetic coils can be coils readily formed from multiple turns of suitable electrical wire or another form of electrical conductor. The electromagnetic coil diameters can be measured as the average diameter across any of the electromagnetic coils in the system. Each electromagnetic coil can have an axis that is perpendicular to the plane in which the electromagnetic coils are wound, and through the center of each electromagnetic coil.

[00087] In embodiments, the Helmholtz-like, very low power electromagnetic coil pair can be defined to be a configuration of two electrical coils that are magnetically aligned north-to-south on the same axis and separated by some distance. The distance of separation can be adjusted to accommodate the shape, thickness, and physical disposition of the tissue to be treated and the surrounding tissues and anatomical structures, but only when the distance between the coils is not limited to.

[00088] The plurality of magnetic square-wave pulses can be generated as a result of the electrical energy discharged through each of the magnetic coils as the pulses are originated from the pulse generator.

[00089] Embodiments can include a kit for therapeutically treating animal tissue ailments including cellular dysfunction of a tissue or an extracellular matrix disruption of a tissue. The kit can include an animal saddlebag with a first pouch and a second pouch connected by a support strap for holding the first pouch and second pouch together across a chest of an animal. The animal can be a four legged animal, such as a dog, a horse, a deer, or another animal.

[00090] A pulse generator can be placed or disposed in one of the pouches. At least one pair of very low power electromagnetic coils can be placed or disposed in another pouch of the saddlebag, enabling the placement of damaged tissue between the magnetic coils.

[00091] The saddlebag can be used to place the electromagnetic coils adjacent to a site of cellular dysfunction or adjacent to a site of tissue having an extracellular matrix disruption. Each pair of electromagnetic coils can be connected to the pulse generator through a power supply conduit.

Embodiments of the kit can include a pet bed for therapeutically treating an animal. The pet bed can include bedding contained in a fabric housing. A Halbach array of electromagnetic coils can be disposed in the fabric housing.

An animal actuated on/off switch can be connected to the Halbach array and to the pulse generator. Magnetic pulse blasts can be generated when an animal actuates the animal actuated on/off switch.

Additionally, the pet bed can contain a heating element connected to a power source of the Halbach array disposed within the fabric housing. The heating element can be controlled by a microcontroller in the fabric housing that can be actuated when the animal engages the animal actuated on/off switch.

The animal actuated on/off switch can be a pressure sensitive switch, a movement sensitive switch, or a heat sensitive switch.

The pet bed can include a cooling element connected to the power source of the Halbach array. The cooling element can be disposed within the fabric housing. The cooling element can be controlled by the microcontroller providing cooling when the animal engages the animal actuated on/off switch.

The pet bed can include pet bedding. Pet bedding can include any of a variety of arrangement of structures which an animal will rest or sleep. For example, a dog bed can have cedar chips as the pet bedding. A horse can have straw as the pet bedding. A cat can have strips of fabric as the pet bedding. The pet bedding can be contained within the fabric housing, such as a corduroy material or canvas, enabling an animal to rest or to sleep.

The electromagnetic coils, the heating and/or cooling elements, and detector switches can be placed within the fabric housing. [000100] Turning now to the Figures, Figure 1 shows an example of a typical pulse blast 61 that approximates a series of bipolar square-waves 62a - 62f usable in a pulse blast with a leading edge 63 and a trailing edge 64. Each pulse can have a duration of between about 0.1 microsecond to about 200 microseconds and has at least one edge with a slew rate of at least 200 kG/s.

[000101] Figure 2 shows an embodiment of two pulse blasts. The first blast 61a is shown consisting of four bipolar pulses with an amplitude yl, a duration xl and a frequency fl . The first blast 61a, as illustrated in Figure 2, is followed by a rest period Rl before the beginning of the second blast 61b. The second blast 61b is shown as 5 unipolar pulses with an amplitude y2, a duration x2 and a frequency f2.

[000102] Figure 2 shows four square -waves 61a, 61b, 61c, and 61d forming a pulse blast.

The first square-wave 61a is shown with a time duration of tl away from the second square -wave 61b. The third square-wave 61c is shown with a time duration t2 equivalent to the time duration between the first and second square-waves. The fourth square -wave 61d is shown with a time t3 duration from the third square -wave which can be double the time durations between the first and second square-waves.

[000103] Figure 3 depicts a pulse generator 10 usable in the embodiments of the system. The pulse generator 10 has a housing 11. In the housing 11 are electronics that generate a plurality of pulse blasts. The pulse generator 10 has a first power supply 16 and a second power supply 17.

[000104] A bi-directional communication and power port 18 flows power 21 into and out of the pulse generator 10, and flows communication signals 19 into and out of the pulse generator 10. The bi-directional communication and power port 18 can be formed in the housing 11 of the pulse generator 10.

[000105] A microcontroller 20 is shown in communication with the bi-directional communication and power port 18. The microcontroller 20 has a processor 22 in communication with either the first power supply 16 or the second power supply 17. The microcontroller 20 also has a data storage 24 in communication with the processor 22. In the data storage 24 are computer instructions 26 with preset pulse parameters.

[000106] Also shown are computer instructions 25 in the data storage for instructing the processor to generate at random intervals, pulse blasts, pulses as the dosage amounts within the specified range of pulse parameters.

[000107] A first pair of transistors 28a and 28b is in communication with the microcontroller

20. A voltage multiplier 30 is connected to the first pair of transistors 28a and 28b. The voltage multiplier 30 has three diodes 32a, 32b, and 32c, as well as three capacitors 34a, 34b, and 34c. The voltage multiplier 30 is in communication with the microcontroller 20 for increasing or decreasing the voltage of electricity of the pulse generator 10.

[000108] A second pair of transistors 36a and 36b are shown connected to the three capacitors

34a, 34b, and 34c. The second pair of transistors 36a and 36b form at least one of a plurality of pulses and/or a pulse blast that are emitted by the pulse generator 10. A pair of power supply conduits 38a and 38b are shown connected to the second pair of transistors 36a and 36b.

[000109] The very low power electromagnetic coil pair 39 are shown connected to the pair of power supply conduits 38a and 38b. The very low power electromagnetic coil pair 39 is sized to generate a plurality of pulse blasts with a slew rate of at least 200 Kilogauss per second (kG/s).

[000110] The very low power electromagnetic coil pair 39 is shown with a first electromagnetic coil 40 with a first electromagnetic coil diameter 44 and a first electromagnetic coil axis 48. A second electromagnetic coil 42 is shown with a second electromagnetic coil diameter 46 and a second electromagnetic coil axis 50.

[000111] Figure 3 also shows an external power supply 65 connected to the second power supply 17 through an on/off switch 66 to allow for uninterrupted pulse blast generation for a dosage amount of time. The on/off switch 66 allows for actuation of the external power supply 65 to supply power to at least the first power supply 16 or second power supply 17.

[000112] Figure 4 shows a detailed view of the very low power electromagnetic coil pair 39.

The first electromagnetic coil 40 with the first electromagnetic coil axis 48 is shown.

[000113] First electromagnetic coil first side 51 with first polarity 52 and first electromagnetic coil second side 53 with second polarity 54 are shown. The coils can be an electromagnetic coils or magnetic coils.

[000114] Also shown is second electromagnetic coil 42 with the second electromagnetic coil axis 50. Second electromagnetic coil first side 55 is shown with first polarity 56, and second electromagnetic coil second side 57 is shown with second polarity 58. The coils can be an electromagnetic coils or magnetic coils.

[000115] Figure 4 shows that each of the electromagnetic coils can be encapsulated with a mechanically flexible polymer coating 74 which allows unimpeded the generation of the magnetic fields.

[000116] Figure 5 shows the orientation of the very low power electromagnetic coil pair for therapeutic treatment. The first electromagnetic coil first side 51 is disposed opposite the second electromagnetic coil second side 57 for treatment of cellular dysfunction of a tissue 100 placed between the first electromagnetic coil 40 and second electromagnetic coil 42; for treatment of an extracellular matrix disruption of a tissue placed between the first and second electromagnetic coils; or combinations of these therapeutic treatments.

[000117] The first electromagnetic coil 40 and second electromagnetic coil 42 can be oriented so that when they are energized using the pulse generator 10, a plurality of magnetic square -wave pulses can be generated with slew rates of at least 200 kG/s for at least a duration from about 0.1 microsecond to about 200 microseconds without forming a sine shaped pulse wave. [000118] Also shown are the first electromagnetic coil second side 53 and second electromagnetic coil first side 55.

[000119] Figure 6 shows an embodiment of the pulse generator 10 with the microcontroller 20 having a processor 22 in communication with at least one network 68 with an administrative server 67, that allows for online reconfiguration of the pulse generator.

[000120] Also shown are the housing 11, the data storage 24, and the computer instructions

26 with preset pulse parameters.

[000121] Figure 7 shows four very low power electromagnetic coil pairs having first electromagnetic coils 40a, 40b, 40c, and 40d paired with second electromagnetic coils 42a, 42b, 42c, and 42d.

[000122] Each electromagnetic coil pair is associated with a pulse generator 10a, 10b, 10c, and lOd. The pulse generators are controlled by a common controller 70.

[000123] The multiple pairs of very low power electromagnetic coils with pulse generators form a magnetic array 69 for treating a large area of tissue 100 that is capable of covering an entire limb, which is a leg in this view.

[000124] Figure 8A shows an embodiment of a kit for therapeutically treating tissue ailments including cellular dysfunction of a tissue or an extracellular matrix disruption of a tissue, with an animal saddlebag 78, a first pouch 79, a pulse generator 10 in the first pouch 79, and a support strap 81.

[000125] Figure 8B shows the opposite side of the animal shown in Figure 8A. The animal saddlebag 78 is shown with a second pouch 80. Within the second pouch 80 is a first electromagnetic coil 40, second electromagnetic coil 42 and first power supply 16.

[000126] The support strap 81 holds the first pouch 79 and second pouch 80 together across the chest of the animal. [000127] Figure 9 shows and embodiment of a pet bed 107. The pet bed has bedding 82, a fabric housing 84 for containing the bedding 82, a Halbach array 85 disposed in the fabric housing 84, and an animal actuated on/off switch 86 connected to the Halbach array 85.

[000128] Also shown are a heating element 88 and a cooling element 92, each connected to a power supply 300 of the pulse generator 10.

[000129] While these embodiments have been described with emphasis on the embodiments, it should be understood that within the scope of the appended claims, the embodiments might be practiced other than as specifically described herein.