MANUFACTURING METHOD AND DEVICE FOR COMPOSITION IN WHICH DISPERSED PHASE IS FINELY DISPERSED INTO CONTINUOUS PHASE

Title:

MANUFACTURING METHOD AND DEVICE FOR COMPOSITION IN WHICH DISPERSED PHASE IS FINELY DISPERSED INTO CONTINUOUS PHASE

Document Type and Number:

WIPO Patent Application WO/2011/068191

Kind Code:

A1

Abstract:

Disclosed is a method whereby a composition in which a dispersed phase is finely dispersed in a continuous phase with low polydispersity can be produced with excellent production efficiency. The composition is manufactured using a manufacturing process comprising the following steps: (A) a swirl flow of a continuous phase liquid is passed through a cylinder configured so that a part or all of the peripheral surface is a porous membrane; (B1) a dispersed phase liquid is supplied to the swirl flow via the porous membrane and dispersed phase particles are formed on the porous membrane; and (B2) the dispersed phase particles formed on the porous membrane are detached by the shear force of the swirl flow. The cylinder has an inflow port for the continuous phase liquid on the peripheral surface near one end of the cylinder and an inlet tube which extends from the inflow port in a direction that is substantially perpendicular to the axis of the cylinder and tangential to the cylinder. It is preferable for step (A) to be configured so that the continuous phase liquid is made to flow in to the cylinder from a direction that is substantially perpendicular to the axis of the cylinder and tangential to the inner wall of the cylinder by means of the inlet tube.

Inventors:

SHIMODA MITSUYA (JP)

Application Number:

PCT/JP2010/071658

Publication Date:

June 09, 2011

Filing Date:

December 03, 2010

Export Citation:

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Assignee:

UNIV KYUSHU NAT UNIV CORP (JP)
SHIMODA MITSUYA (JP)

International Classes:

A61K8/06; B01F25/46; B01J13/00; C08F2/22; C09K23/00

Domestic Patent References:

WO2008038763A1

2008-04-03

Foreign References:

JP2003335804A	2003-11-28
JPH05123570A	1993-05-21
JP2007111616A	2007-05-10
JP2005162848A	2005-06-23
JPH0295433A	1990-04-06
JPS5712822A	1982-01-22
JP2003270849A	2003-09-25
JPH0295433A	1990-04-06

Other References:

JOURNAL OF MEMBRANE SCIENCE, vol. 299, 2007, pages 190 - 199
MASATO KUKIZAKI: "Preparation of Porous Glass Membrane and Its Application to Monodisperse Emulsions and Nanobubble", MIYAZAKI PREFECTURE INDUSTRIAL TECHNOLOGY CENTER
MASATO KUKIZAKI: "Preparation of Porous Glass Membrane and Its Application to Monodisperse Emulsions and Nanobubbles", MIYAZAKI PREFECTURE INDUSTRIAL TECHNOLOGY CENTER
TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS, vol. 58, no. 550, 1992, pages 1668 - 1673