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Title:
MANUFACTURING METHOD FOR MEDICAL EQUIPMENT FOR REDUCING PLATELET ADHESION OF A SURFACE IN CONTACT WITH BLOOD
Document Type and Number:
WIPO Patent Application WO/2012/036238
Kind Code:
A1
Abstract:
A manufacturing method for medical equipment wherein an electron beam is irradiated on a titanium or titanium alloy substrate surface that has at least been machined, and the platelet adhesion of a surface which is in contact with blood is reduced; and a manufacturing method for medical equipment that uses a specific pre-processing method and an electron beam irradiation method to reduce the platelet adhesion of a surface which is in contact with blood, and which suppresses the formation of minute depressions (craters) in the surface, which can occur due to the irradiation of an electron beam.

Inventors:
MORI TAKEHISA (JP)
OKAWA ATSUSHI (JP)
TSUBOUCHI TAKESHI (JP)
UEMURA KENSUKE (JP)
Application Number:
PCT/JP2011/071110
Publication Date:
March 22, 2012
Filing Date:
September 15, 2011
Export Citation:
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Assignee:
TERUMO CORP (JP)
NAGATA SEIKI KK (JP)
MORI TAKEHISA (JP)
OKAWA ATSUSHI (JP)
TSUBOUCHI TAKESHI (JP)
UEMURA KENSUKE (JP)
International Classes:
A61M1/10; A61L31/00; A61N1/362
Foreign References:
JPH10248923A1998-09-22
JP2010068935A2010-04-02
JP2009279268A2009-12-03
JPH11506807A1999-06-15
JP2010000295A2010-01-07
JP2005270345A2005-10-06
JP2005287598A2005-10-20
Other References:
LIN Z. ET AL.: "Influence of Chemical Composition and Structure on the Blood Compatibility of Titanium Oxide Films Prepared by E-beam Evaporation.", PROCEEDINGS OF THE ANNUAL TECHNICAL CONFERENCE., vol. 51, 2008, pages 223 - 228, XP055137296
YOSHIYUKI UNO ET AL.: "High Efficiency Finishing of Biomaterial Titanium Alloy by Wide-area Electron Beam Irradiation", THE JAPAN SOCIETY OF MECHANICAL ENGINEERS MANUFACTURING & MACHINE TOOL DIVISION KOENKAI KOEN RONBUNSHU, vol. 5, 2004, pages 279 - 280, XP008171696
KAZUMICHI WAKABAYASHI ET AL.: "Surface Modification of Dental Alloy by Electron-Beam System (Part 1) : Change of Surface Roughness", THE JOURNAL OF THE JAPANESE SOCIETY FOR DENTAL MATERIALS AND DEVICES, vol. 23, no. 2, 2004, pages 177, XP008171626
JUNKO TOKUNAGA ET AL.: "Surface modification of dental alloy by electron-beam system (Part 4) : Examination on the surface of Titanium and Au-Ag-Pd alloy", THE JOURNAL OF THE JAPANESE SOCIETY FOR DENTAL MATERIALS AND DEVICES, vol. 24, no. 5, 2005, pages 407, XP008171624
TOKUNAGA J. ET AL.: "Large-area electron beam irradiation for surface polishing of cast titanium.", DENTAL MATERIALS JOURNAL, vol. 28, no. 5, 2009, pages 571 - 577, XP055075476
OKADA A. ET AL.: "New Surface Modification Method of Bio-Titanium Alloy by EB Polishing.", JOURNAL OF ADVANCED MECHANICAL DESIGN, SYSTEMS, AND MANUFACTURING (WEB), vol. 2, no. 4, 2008, pages 694 - 700, XP055075477
JONES M.I. ET AL.: "Protein adsorption and platelet attachment and activation, on TiN, TiC, and DLC coatings on titanium for cardiovascular applications.", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, vol. 52, no. 2, 2000, pages 413 - 421, XP055075478
See also references of EP 2617441A4
Attorney, Agent or Firm:
WATANABE Mochitoshi et al. (JP)
Mochitoshi Watanabe (JP)
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Claims: