Title:
MARKER AND METHOD FOR DETECTING INFLAMMATION-RELATED DISEASES
Document Type and Number:
WIPO Patent Application WO/2024/103504
Kind Code:
A1
Abstract:
The present application relates to a marker and a method for detecting inflammation-related diseases. The marker of the present application can stably exist in an ex vivo body fluid sample and does not gather on a cell membrane, so the detection result is very accurate. The marker can be widely applied to the medical detection of inflammation-related diseases, having good clinical application prospects.
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Inventors:
WANG JIANXIA (CN)
LI JUN (CN)
LIU YING (CN)
KANG HAOXIANG (CN)
MAO SUFANG (CN)
CAO YU (CN)
LI JUN (CN)
LIU YING (CN)
KANG HAOXIANG (CN)
MAO SUFANG (CN)
CAO YU (CN)
Application Number:
PCT/CN2022/144118
Publication Date:
May 23, 2024
Filing Date:
December 30, 2022
Export Citation:
Assignee:
BEIJING MDTK BIOTECHNOLOGY CO LTD (CN)
International Classes:
C07K14/47; A61K39/395; A61K45/00; A61P29/00; A61P31/04; A61P31/12; C07K16/18; C12N5/20; C12N15/13; G01N33/569; G01N33/577; G01N33/68
Foreign References:
| US20110093962A1 | 2011-04-21 | |||
| CN114401987A | 2022-04-26 | |||
| US20120028266A1 | 2012-02-02 | |||
| CN111793632A | 2020-10-20 | |||
| CN111735968A | 2020-10-02 |
Other References:
DONGPING ZHANG: "Gasdermin D serves as a key executioner of pyroptosis in experimental cerebral ischemia and reperfusion model both in vivo and in vitro", JOURNAL OF NEUROSCIENCE RESEARCH, WILEY-LISS, US, vol. 97, no. 6, 1 June 2019 (2019-06-01), US , pages 645 - 660, XP093169847, ISSN: 0360-4012, DOI: 10.1002/jnr.24385
MINGWEI SUN: "Comprehensive Analysis of Protein N-Terminome by Guanidination of Terminal Amines", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 92, no. 1, 7 January 2020 (2020-01-07), US , pages 567 - 572, XP093169851, ISSN: 0003-2700, DOI: 10.1021/acs.analchem.9b04141
LI, ZILIN ET AL.: "Shigella Evades Pyroptosis by Arginine ADP-riboxanation of Caspase-11", NATURE., vol. 599, no. 7884, 20 October 2021 (2021-10-20), XP037643172, DOI: 10.1038/s41586-021-04020-1
MINGWEI SUN: "Comprehensive Analysis of Protein N-Terminome by Guanidination of Terminal Amines", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 92, no. 1, 7 January 2020 (2020-01-07), US , pages 567 - 572, XP093169851, ISSN: 0003-2700, DOI: 10.1021/acs.analchem.9b04141
LI, ZILIN ET AL.: "Shigella Evades Pyroptosis by Arginine ADP-riboxanation of Caspase-11", NATURE., vol. 599, no. 7884, 20 October 2021 (2021-10-20), XP037643172, DOI: 10.1038/s41586-021-04020-1
Attorney, Agent or Firm:
HUIP PATENT ATTORNEYS (CN)
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