Title:
MASS-SPECTROMETRY-IMAGING-DATA PROCESSING DEVICE AND METHOD
Document Type and Number:
WIPO Patent Application WO/2018/037569
Kind Code:
A1
Abstract:
In the present invention, a user designates regions of interest (ROIs), such as a region believed to contain a large amount of a compound the user wants to identify and a region where the compound and another compound overlap, on one or a plurality of specific MS imaging images and instructs that the ROIs be added or subtracted. Then, for each designated ROI, an average MS/MS spectrum is calculated from the MS/MS spectrum data for each measurement point included in the region, and an MS/MS spectrum resulting from addition or subtraction of the average MS/MS spectrums of the ROIs is calculated. ROI addition makes it possible to enhance the intensity of a peak originating from a target compound. Meanwhile, ROI subtraction makes it possible to remove peaks originating from other compounds overlapping the target compound. Identifying the target compound by using the MS/MS spectrum resulting from this addition or subtraction for library searching increases spectral similarity scores compared to the prior art and makes it possible to enhance identification accuracy.
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Inventors:
IKEGAMI MASAHIRO (JP)
OGATA KORETSUGU (JP)
OGATA KORETSUGU (JP)
Application Number:
PCT/JP2016/075094
Publication Date:
March 01, 2018
Filing Date:
August 26, 2016
Export Citation:
Assignee:
SHIMADZU CORP (JP)
International Classes:
G01N27/62
Domestic Patent References:
WO2014175211A1 | 2014-10-30 | |||
WO2008126151A1 | 2008-10-23 | |||
WO2014128912A1 | 2014-08-28 | |||
WO2016002047A1 | 2016-01-07 |
Foreign References:
JP2013040808A | 2013-02-28 | |||
JP2014215043A | 2014-11-17 | |||
JP2012237753A | 2012-12-06 | |||
JP2016075574A | 2016-05-12 |
Other References:
"iMScope TRIO Imaging mass microscope", 22 June 2016, SHIMADZU CORPORATION
See also references of EP 3505923A4
See also references of EP 3505923A4
Attorney, Agent or Firm:
KYOTO INTERNATIONAL PATENT LAW OFFICE (JP)
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