Title:
MATERIAL-FIXING SUBSTRATE AND METHOD FOR PRODUCING SAME, AND MATERIAL-FIXING AGENT USED FOR MATERIAL-FIXING SUBSTRATE
Document Type and Number:
WIPO Patent Application WO/2017/212838
Kind Code:
A1
Abstract:
Provided is a material-fixing substrate wherein copper does not have to be used as a catalyst since a cyclic alkyne is provided at a substrate-binding region where a covalent bond is formed to a surface of the substrate, and therefore, for example, when a material to be fixed is a cell, damage to the cell can be reduced. This material-fixing substrate has a to-be-fixed material fixed thereon by a material-fixing agent, wherein the material-fixing agent comprises: a substrate-binding region which forms a covalent bond to the surface of the substrate, and has at least a cyclic alkyne; a hydrophilic region to be bonded to the substrate-binding region; a light-responsive region to be bonded to the hydrophilic region, and the backbone of which is changed by irradiation with light; and an adhesion region to which the material to be fixed adheres.
Inventors:
SUWA SHUNICHI (JP)
NAGAMINE KUNIHIKO (JP)
MATSUMOTO MASAHIRO (JP)
YAMAGUCHI DAISUKE (JP)
GOTO YOSHIO (JP)
YOSHIMITSU KYOHEI (JP)
NAGAMINE KUNIHIKO (JP)
MATSUMOTO MASAHIRO (JP)
YAMAGUCHI DAISUKE (JP)
GOTO YOSHIO (JP)
YOSHIMITSU KYOHEI (JP)
Application Number:
PCT/JP2017/017263
Publication Date:
December 14, 2017
Filing Date:
May 02, 2017
Export Citation:
Assignee:
SONY CORP (JP)
International Classes:
C07K17/00; G01N33/48
Foreign References:
| JP2011504507A | 2011-02-10 |
Other References:
VASELLI, E. ET AL.: "RGD Signaling Using Azobenzene Photoswitch-Modified Surfaces", CHEMPLUSCHEM, vol. 80, no. 10, 2015, pages 1547 - 1555, XP055456933
MUSHOKUBAI CLICK HANNO SOSHI KOKINOSEI ALKIN, April 2016 (2016-04-01), pages 1 - 4, Retrieved from the Internet [retrieved on 20170707]
AGARD, N. J. ET AL.: "A Strain-Promoted [3+2] Azide-Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 126, no. 46, 2004, pages 15046 - 15047, XP002362785
ATSUSHI SHIMOYAMA: "Kininatta Ronbun", SEIMEI KAGAKU KENKYU LETTER, vol. 34, 2010, pages 16 - 20
NING, X. ET AL.: "Visualizing Metabolically Labeled Glycoconjugates of Living Cells by Copper-Free and Fast Huisgen Cycloadditions", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 47, no. 12, 2008, pages 2253 - 2255, XP002659161
SONO NI AZIDE TO ALKYNE TONO CLICK HANNO : YUKI KAGAKU HANNO GA MOTARASHITA SEIMEI KAGAKU KENKYU NI OKERU KAKUSHIN, 31 May 2016 (2016-05-31), Retrieved from the Internet [retrieved on 20170707]
MONTANEZ, M. I. ET AL.: "Bifunctional Dendronized Cellulose Surfaces as Biosensors", BIOMACROMOLECULES, vol. 12, no. 6, 2011, pages 2114 - 2125, XP055456943
KIM, D.-Y. ET AL.: "Photoresponsive Carbohydrate-based Giant Surfactants: Automatic Vertical Alignment of Nematic Liquid Crystal for the Remote-Controllable Optical Device", ACS APPLIED MATERIALS & INTERFACES, vol. 7, no. 11, 4 March 2015 (2015-03-04), pages 6195 - 6204, XP055456948
SAITO, F. ET AL.: "Critical Evaluation and Rate Constants of Chemoselective Ligation Reactions for Stoichiometric Conjugations in Water", ACS CHEMICAL BIOLOGY, vol. 10, no. 4, 2015, pages 1026 - 1033, XP055328644
MUSHOKUBAI CLICK HANNO SOSHI KOKINOSEI ALKIN, April 2016 (2016-04-01), pages 1 - 4, Retrieved from the Internet
AGARD, N. J. ET AL.: "A Strain-Promoted [3+2] Azide-Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 126, no. 46, 2004, pages 15046 - 15047, XP002362785
ATSUSHI SHIMOYAMA: "Kininatta Ronbun", SEIMEI KAGAKU KENKYU LETTER, vol. 34, 2010, pages 16 - 20
NING, X. ET AL.: "Visualizing Metabolically Labeled Glycoconjugates of Living Cells by Copper-Free and Fast Huisgen Cycloadditions", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 47, no. 12, 2008, pages 2253 - 2255, XP002659161
SONO NI AZIDE TO ALKYNE TONO CLICK HANNO : YUKI KAGAKU HANNO GA MOTARASHITA SEIMEI KAGAKU KENKYU NI OKERU KAKUSHIN, 31 May 2016 (2016-05-31), Retrieved from the Internet
MONTANEZ, M. I. ET AL.: "Bifunctional Dendronized Cellulose Surfaces as Biosensors", BIOMACROMOLECULES, vol. 12, no. 6, 2011, pages 2114 - 2125, XP055456943
KIM, D.-Y. ET AL.: "Photoresponsive Carbohydrate-based Giant Surfactants: Automatic Vertical Alignment of Nematic Liquid Crystal for the Remote-Controllable Optical Device", ACS APPLIED MATERIALS & INTERFACES, vol. 7, no. 11, 4 March 2015 (2015-03-04), pages 6195 - 6204, XP055456948
SAITO, F. ET AL.: "Critical Evaluation and Rate Constants of Chemoselective Ligation Reactions for Stoichiometric Conjugations in Water", ACS CHEMICAL BIOLOGY, vol. 10, no. 4, 2015, pages 1026 - 1033, XP055328644
Attorney, Agent or Firm:
WATANABE Kaoru (JP)
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