Title:
MATERIALS CONTAINING MULTIPLE LAYERS OF VESICLES
Document Type and Number:
WIPO Patent Application WO2003075888
Kind Code:
A3
Abstract:
The present invention provides a composite material, preferably an opthalmic device, more preferably a contact lens, which comprises a vesicle-containing coating including at least one layer of a vesicle and one layer of a polyionic material having charges opposite the charges of the vesicle. Such composite material can find use in biomedical applications, for example, a device for localized drug delivery and an in vivo analyte sensor such as glucose sensing contact lens. By lifting off the vesicle-containing coating from a substrate, a self-standing membrane (film) capable of encapsulating a wide variety of guest materials can be prepared. In addition, the invention provides methods for making vesicle-containing composite and film materials of the present invention.
Inventors:
LALLY JOHN MARTIN (US)
KOTOV NICHOLAS (US)
KOTOV NICHOLAS (US)
Application Number:
PCT/EP2003/002564
Publication Date:
March 04, 2004
Filing Date:
March 12, 2003
Export Citation:
Assignee:
NOVARTIS AG (CH)
NOVARTIS PHARMA GMBH (AT)
LALLY JOHN MARTIN (US)
KOTOV NICHOLAS (US)
NOVARTIS PHARMA GMBH (AT)
LALLY JOHN MARTIN (US)
KOTOV NICHOLAS (US)
International Classes:
A61F9/00; A61K9/127; G02C7/04; A61K48/00; A61P43/00; G02B1/04; (IPC1-7): A61K9/127; A61B5/00
Domestic Patent References:
| WO2001057118A2 | 2001-08-09 | |||
| WO2001072878A1 | 2001-10-04 |
Foreign References:
| EP0472990A2 | 1992-03-04 |
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