Title:
MEDICAL BASE MATERIAL FOR INDWELLING CARDIOVASCULAR DEVICE
Document Type and Number:
WIPO Patent Application WO/2020/158847
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a medical base material for an indwelling cardiovascular device, wherein a special knitted structure, which is formed of multifilaments containing ultrafine fibers, can maintain antithrombotic properties by early endothelialization and the storage property in a sheath catheter and the mechanical strength are improved. The present invention provides a medical base material for an indwelling cardiovascular device, said medical base material comprising a knitted fabric, which is formed of multifilaments comprising 30 wt% or more of ultrafine fibers having a single fiber diameter of 1-10 μm, and heparin, a heparin derivative or a pharmacologically acceptable salt thereof which is chemically bonded to the surface of the ultrafine fibers, wherein the knitted fabric has a basis weight of from 5 mg/cm2 to 20 mg/cm2 and a thickness of 200 μm or less and shows a water permeability under a pressure of 120 mmHg of from 1000 mL/min/cm2 to 10000 mL/min/cm2.
Inventors:
KAKIYAMA SO (JP)
YAMADA SATOSHI (JP)
TANAKA NOBUAKI (JP)
TANAHASHI KAZUHIRO (JP)
YAMADA SATOSHI (JP)
TANAKA NOBUAKI (JP)
TANAHASHI KAZUHIRO (JP)
Application Number:
PCT/JP2020/003358
Publication Date:
August 06, 2020
Filing Date:
January 30, 2020
Export Citation:
Assignee:
TORAY INDUSTRIES (JP)
International Classes:
D04B1/16; A61B17/12; A61F2/01; A61F2/04; A61L33/10; D04B21/16; D06M15/03
Domestic Patent References:
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Other References:
NOISHIKI, Y, Y. YAMANE, T. OOKOSHI, Y. TOMIZAWA, E. TONOKURA: "DEVELOPMENT OF A KNITTED FABRIC VASCULAR PROSTHESIS IMPREGNATED WITH ULTRAFINE POLYESTER FIBERS", JINKO ZOKI, vol. 28, no. 1, 15 February 1999 (1999-02-15), pages 278 - 283, XP055828625, ISSN: 0300-0818, DOI: 10.11392/jsao1972.28.278
INOUE, MARI: "Research on the Mechanics of Fibrous Materials", JOURNAL OF THE SOCIETY OF FIBER SCIENCE AND TECHNOLOGY, vol. 64, no. 8, 30 September 2008 (2008-09-30), pages 246 - 251, XP055828627, ISSN: 0037-9875, DOI: 10.2115/fiber.64.P_246
MAREK GRYGIER ET AL., ADVANCES IN INTERVENTIONAL CARDIOLOGY, vol. 13, no. 42, 2017, pages 62 - 66
See also references of EP 3919664A4
INOUE, MARI: "Research on the Mechanics of Fibrous Materials", JOURNAL OF THE SOCIETY OF FIBER SCIENCE AND TECHNOLOGY, vol. 64, no. 8, 30 September 2008 (2008-09-30), pages 246 - 251, XP055828627, ISSN: 0037-9875, DOI: 10.2115/fiber.64.P_246
MAREK GRYGIER ET AL., ADVANCES IN INTERVENTIONAL CARDIOLOGY, vol. 13, no. 42, 2017, pages 62 - 66
See also references of EP 3919664A4
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