Title:
MEDICAL DEVICES
Document Type and Number:
WIPO Patent Application WO/2009/118531
Kind Code:
A3
Abstract:
A medical device having body contacting surfaces provided with a film of amorphous calcium phosphate having a thickness of 1 nm to 10000 nm and an average dissolution rate calculated as the time taken to remove 95% of the film of at least 1 nm h-1 as determined in accordance with ASTM Standard P1926-03. The characteristics of the film are such that the film is relatively rapidly dissolved from the surface by body fluids. This dissolution of the surface film of amorphous calcium phosphate is sufficiently fast to prevent the attachment of bacteria, thus preventing them forming a biofilm and keeping the cells in a planktonic (non-biofilm) state where they are more vulnerable to the body's defences. The invention is particularly applicable to implants (e.g. orthopaedic implants such as prosthetic hips) but may also be applied to "non-implanted" devices such as surgical instruments.
Inventors:
GRANT DAVID MALCOLM (GB)
BOTTERILL NICHOLAS WILLIAM (GB)
BOTTERILL NICHOLAS WILLIAM (GB)
Application Number:
PCT/GB2009/000805
Publication Date:
July 15, 2010
Filing Date:
March 26, 2009
Export Citation:
Assignee:
EMINATE LTD (GB)
GRANT DAVID MALCOLM (GB)
BOTTERILL NICHOLAS WILLIAM (GB)
GRANT DAVID MALCOLM (GB)
BOTTERILL NICHOLAS WILLIAM (GB)
International Classes:
A61L27/32; A61L27/58
Domestic Patent References:
| WO2000033895A1 | 2000-06-15 |
Foreign References:
| US20060210494A1 | 2006-09-21 | |||
| US20020038149A1 | 2002-03-28 |
Attorney, Agent or Firm:
ATKINSON, Peter, Birch (Sussex House83-85 Mosley Street, Manchester M2 3LG, GB)
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