MEDICAL HYDROGEL COMPOSITION, AND MEDICAL HYDROGEL, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

Title:

MEDICAL HYDROGEL COMPOSITION, AND MEDICAL HYDROGEL, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

Document Type and Number:

WIPO Patent Application WO/2017/186168

Kind Code:

A1

Abstract:

A medical hydrogel composition, a medical hydrogel, a preparation method therefore and an application thereof, and a medical hydrogel kit. The medical hydrogel composition comprises a first component and a second component; the first component comprises polylysine and polyethyleneimine; the second component comprises one or more of 4-arm-polyethylene glycol-succinimidyl glutarate, 4-arm-polyethylene glycol-succinimidyl succinate, and 4-arm-polyethylene glycol-succinimidyl carbonate; the degree of polymerization of the polylysine is 20 or more. The medical hydrogel is formed by reacting the first component with the second component of the medical hydrogel composition. The medical hydrogel kit comprises the medical hydrogel composition and a buffer solution used for dissolving the components of the medical hydrogel composition. The medical hydrogel has a degree of swelling of -10-50%, and can be applied in narrow parts where cranial, spinal and peripheral nerves are densely distributed.

Inventors:

LIN LIMIN (CN)
YANG YAYA (CN)
MA CHENG (CN)
DENG KUNXUE (CN)
YUAN YUYU (CN)

Application Number:

PCT/CN2017/082425

Publication Date:

November 02, 2017

Filing Date:

April 28, 2017

Export Citation:

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Assignee:

MEDPRIN REGENERATIVE MEDICAL TECH CO LTD (CN)

International Classes:

A61L26/00; A61L27/52; A61L27/26; A61L31/04; A61L31/06; A61L31/14

Foreign References:

CN105963792A	2016-09-28
CN102911493A	2013-02-06
US20100297235A1	2010-11-25
CN105169469A	2015-12-23
CN101843925A	2010-09-29

Other References: