Title:
MEDICAL SHEET
Document Type and Number:
WIPO Patent Application WO/2021/145362
Kind Code:
A1
Abstract:
The present invention provides a medical sheet which comprises nonwoven fabric formed of fibers containing aliphatic polyester, has a void ratio of 50-90%, and has cell infiltration-suppressing action. The sheet according to the present invention is very useful because the sheet has excellent neuroprotection and/or neuroregeneration actions which protect nerves by suppressing the infiltration of inflammatory cells such as macrophages and do not have a stimulation having an adverse effect on a nerve in order to allow body fluids to pass through the sheet by winding the sheet around the nerve of damaged peripheral nerve area.
Inventors:
KONISHI TAKAFUMI (JP)
NAIKI MITSURU (JP)
UJITA TOSHIKO (JP)
YAMAMOTO HITOSHI (JP)
NAIKI MITSURU (JP)
UJITA TOSHIKO (JP)
YAMAMOTO HITOSHI (JP)
Application Number:
PCT/JP2021/000985
Publication Date:
July 22, 2021
Filing Date:
January 14, 2021
Export Citation:
Assignee:
NIPPON ZOKI PHARMACEUTICAL CO (JP)
International Classes:
A61L31/06; A61F13/00; A61K9/70; A61K31/714; A61L15/26; A61L15/44; A61L27/18; A61L27/54; A61L27/58; A61L31/14; A61L31/16; A61L33/06; A61P25/00
Domestic Patent References:
| WO2017154822A1 | 2017-09-14 |
Foreign References:
| JP2010115393A | 2010-05-27 |
Other References:
CHEN, LIANG ET AL.: "Preparation of electrospun nanofibers with desired microstructures using a programmed three-dimensional (3D) nanofiber collector", MATERIALS SCIENCE & ENGINEERING C, vol. 106, no. 110188, 10 September 2019 (2019-09-10), pages 1 - 10, XP085913028, DOI: 10.1016/j.msec.2019.110188
SARHANE, KARIM A. ET AL.: "Macroporous nanofiber wraps promote axonal regeneration and functional recovery in nerve repair by limiting fibrosis", ACTA BIOMATERIALIA, vol. 88, 23 February 2019 (2019-02-23), pages 332 - 345, XP055843267
See also references of EP 4091643A4
SARHANE, KARIM A. ET AL.: "Macroporous nanofiber wraps promote axonal regeneration and functional recovery in nerve repair by limiting fibrosis", ACTA BIOMATERIALIA, vol. 88, 23 February 2019 (2019-02-23), pages 332 - 345, XP055843267
See also references of EP 4091643A4
Attorney, Agent or Firm:
FUJII, Ikuro et al. (JP)
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