MEDICAL USE OF TRIFLURIDINE OR TRIFLURIDINE TIPIRACIL COMPOSITION

Title:

MEDICAL USE OF TRIFLURIDINE OR TRIFLURIDINE TIPIRACIL COMPOSITION

Document Type and Number:

WIPO Patent Application WO/2020/215999

Kind Code:

A1

Abstract:

Use of trifluridine or a trifluridine tipiracil composition in the preparation of a medicament for treating blood diseases. Specifically involved is use in the preparation of a medicament for treating blood diseases caused by a β-hemoglobin gene defect or gene mutation. The trifluridine tipiracil composition consists of trifluridine and tipiracil, and the weight ratio thereof is 1:1-4:1. Said composition can also be prepared with a pharmaceutically acceptable carrier into a pharmaceutical composition for preparing a medicament for treating blood diseases.

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Inventors:

ZHANG RUOWEN (US)
ZHOU DEWANG (US)

Application Number:

PCT/CN2020/082054

Publication Date:

October 29, 2020

Filing Date:

March 30, 2020

Export Citation:

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Assignee:

ZHANG RUOWEN (CN)
ZHOU DEWANG (US)

International Classes:

A61K31/7072; A61K31/513; A61P7/00; A61P7/06

Domestic Patent References:

WO2017185062A1

2017-10-26

Foreign References:

CN109999053A	2019-07-12
CN104761603A	2015-07-08
CN103108625A	2013-05-15

Other References:

KWAKMAN, JOHANNES J. M. ET AL.: "Feasibility and effectiveness of trifluridine/tipiracil in metastatic colorectal cancer: real life data from The Netherlands", INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, vol. 23, 4 December 2017 (2017-12-04), pages 482 - 489, XP036502918, DOI: 10.1007/s10147-017-1220-0
"TAS-102 (Non-official translation: TAS-102 can significantly improve the survival rate of patients with metastatic colorectal cancer", CHINESE JOURNAL OF COLORECTAL DISEASES (ELECTRONIC EDITION, vol. 4, no. 4, 31 December 2015 (2015-12-31), pages 28

Attorney, Agent or Firm:

SHENYANG FEIYANG LINGRUI INTELLECTUAL PROPERTY AGENCY (GENERAL PARTNERSHIP) (CN)

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