Title:
MEDICAMENT FOR TREATMENT AND/OR PREVENTION OF CANCER
Document Type and Number:
WIPO Patent Application WO/2024/043257
Kind Code:
A1
Abstract:
This medicament is useful for treatment and/or prevention of a cancer, said medicament containing a RET kinase inhibitor and an antibody or fragment thereof together or separately, said antibody or fragment thereof having immunological reactivity with a CAPRIN-1 protein.
Inventors:
WASAI UKEI (JP)
OKANO FUMIYOSHI (JP)
SAITO TAKANORI (JP)
OKANO FUMIYOSHI (JP)
SAITO TAKANORI (JP)
Application Number:
PCT/JP2023/030237
Publication Date:
February 29, 2024
Filing Date:
August 23, 2023
Export Citation:
Assignee:
TORAY INDUSTRIES (JP)
International Classes:
A61K39/395; A61K31/4995; A61K45/00; A61P35/00; A61P35/02; A61P43/00; C07K16/28
Domestic Patent References:
| WO2021182573A1 | 2021-09-16 |
Other References:
YAMADA, KAZUHIKO: "Multi-target molecular targeted drug", JAPANESE JOURNAL OF CLINICAL MEDICINE, vol. 67, no. 1, Spec. Iss., 1 January 2009 (2009-01-01), JP , pages 301 - 305, XP009552997, ISSN: 0047-1852
NISHIOKA, YASUHIKO, SONE, SABURO: "Molecularly targeted therapeutic drugs that target multiple molecules", JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, BIOMEDICAL DRUGS PUBLICATION, JP, vol. 224, no. 13, 1 January 2008 (2008-01-01), JP , pages 1114 - 1117, XP009552943, ISSN: 0039-2359
NISHIO MAKOTO: "Targeting RET Fusion Genes -Translation to Personalized Lung Cancer Therapy", JAPANESE JOURNAL OF LUNG CANCER, JAPAN LUNG CANCER SOCIETY, CHIBA, JP, vol. 55, no. 6, 6 October 2015 (2015-10-06), JP , pages 885 - 888, XP093144631, ISSN: 0386-9628
NISHIO, MAKOTO : "Efficacy and safety of selpercatinib on non-small cell lung cancer with positive RET fusion genes: Analysis and results of Japanese cohort in joint international phase I and phase II clinical trials", JAPANESE JOURNAL OF CANCER AND CHEMOTHERAPY, vol. 49, no. 6, 1 June 2022 (2022-06-01), JP , pages 669 - 675, XP009553344, ISSN: 0385-0684
NISHIOKA, YASUHIKO, SONE, SABURO: "Molecularly targeted therapeutic drugs that target multiple molecules", JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, BIOMEDICAL DRUGS PUBLICATION, JP, vol. 224, no. 13, 1 January 2008 (2008-01-01), JP , pages 1114 - 1117, XP009552943, ISSN: 0039-2359
NISHIO MAKOTO: "Targeting RET Fusion Genes -Translation to Personalized Lung Cancer Therapy", JAPANESE JOURNAL OF LUNG CANCER, JAPAN LUNG CANCER SOCIETY, CHIBA, JP, vol. 55, no. 6, 6 October 2015 (2015-10-06), JP , pages 885 - 888, XP093144631, ISSN: 0386-9628
NISHIO, MAKOTO : "Efficacy and safety of selpercatinib on non-small cell lung cancer with positive RET fusion genes: Analysis and results of Japanese cohort in joint international phase I and phase II clinical trials", JAPANESE JOURNAL OF CANCER AND CHEMOTHERAPY, vol. 49, no. 6, 1 June 2022 (2022-06-01), JP , pages 669 - 675, XP009553344, ISSN: 0385-0684
Download PDF: