Title:
MEDICINAL COMPOSITION COMPRISING ESCITALOPRAM
Document Type and Number:
WIPO Patent Application WO/2018/190294
Kind Code:
A1
Abstract:
The present invention mainly addresses the problem of providing a novel medicinal composition which comprises escitalopram as an active ingredient and has secured stability (light stability and heat stability) as a medicine. The present invention includes, for example: a medicinal composition characterized by comprising escitalopram or a salt thereof and iron oxide; a method for manufacturing a medicinal composition, said method being characterized by comprising a step for granulating a mixture which contains particles of escitalopram or a salt thereof having an average particle diameter D50 of 40 μm or less and mannitol; and granules characterized by comprising a core particle containing escitalopram or a salt thereof and an excipient and a coating layer containing ethyl cellulose.
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Inventors:
TOKITO MASAKAZU (JP)
HONJO TATSUYA (JP)
NAKAMURA TATSURO (JP)
TAKAHASHI KYOSUKE (JP)
OKUDA YUTAKA (JP)
HONJO TATSUYA (JP)
NAKAMURA TATSURO (JP)
TAKAHASHI KYOSUKE (JP)
OKUDA YUTAKA (JP)
Application Number:
PCT/JP2018/014919
Publication Date:
October 18, 2018
Filing Date:
April 09, 2018
Export Citation:
Assignee:
TOWA PHARMACEUTICAL CO LTD (JP)
International Classes:
A61K31/343; A61K9/16; A61K9/20; A61K47/02; A61K47/26; A61K47/38; A61P25/24; C07D307/87
Foreign References:
| CN106176691A | 2016-12-07 | |||
| JP2015178482A | 2015-10-08 | |||
| JP2015147821A | 2015-08-20 | |||
| JP2011126906A | 2011-06-30 | |||
| JP2009519969A | 2009-05-21 | |||
| JP2011520798A | 2011-07-21 | |||
| JP2005525993A | 2005-09-02 | |||
| US20160008375A1 | 2016-01-14 |
Attorney, Agent or Firm:
SHIMIZU Naoto (JP)
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