Title:
MEDICINAL COMPOSITION FOR PERIODONTAL POCKET ADMINISTRATION CONTAINING BISPHOSPHONIC ACID DERIVATIVE OR ITS SALT AS THE ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2004/019957
Kind Code:
A1
Abstract:
A medicinal composition for periodontal pocket administration containing a bisphosphonic acid derivative as the active ingredient which has excellent sustained release properties in topical administration. This medicinal composition for periodontal pocket administration contains a bisphosphonic acid derivative or its salt and a base which undergoes liquid-gel phase transition upon contact with a physiological body fluid in the periodontal pocket.
Inventors:
YOSHII RYOJI (JP)
AOKI TAKAO (JP)
AOKI TAKAO (JP)
Application Number:
PCT/JP2003/010940
Publication Date:
March 11, 2004
Filing Date:
August 28, 2003
Export Citation:
Assignee:
TORAY INDUSTRIES (JP)
YOSHII RYOJI (JP)
AOKI TAKAO (JP)
YOSHII RYOJI (JP)
AOKI TAKAO (JP)
International Classes:
A61K9/00; A61K31/663; A61K47/36; A61P1/02; A61P19/08; A61P43/00; (IPC1-7): A61K31/663; A61K9/06; A61K47/34; A61K47/36; A61K47/46; A61P1/02; A61P19/08; A61P43/00
Domestic Patent References:
WO2001005403A1 | 2001-01-25 | |||
WO1994008562A1 | 1994-04-28 |
Foreign References:
JP2000095677A | 2000-04-04 | |||
US5143934A | 1992-09-01 |
Other References:
EUR. J. PHARM. SCI., vol. 14, no. 1, 2001, pages 53 - 61, XP002973980
INT. J. PHARM., vol. 142, 1996, pages 9 - 23, XP002973981
INT. J. PHARM., vol. 142, 1996, pages 9 - 23, XP002973981
Attorney, Agent or Firm:
Tanigawa, Hidejiro c/o TANIGAWA & ASSOCIATES (Patent Firm 6F, Iwata Bldg., 5-12, Iidabashi 4-chom, Chiyoda-ku Tokyo, JP)
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