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Title:
MEDICINAL COMPOSITIONS AGAINST HELICOBACTER PYLORI
Document Type and Number:
WIPO Patent Application WO/1998/051306
Kind Code:
A1
Abstract:
Medicinal compositions against $i(Helicobacter pylori), which contain as the active ingredient a 1-hydroxy-3-methyl-quinolone derivative represented by formula (I) or its pharmaceutically acceptable salt. Because of having an antibacterial effect on $i(H. pylori), the above compound is useful in treating or preventing infection of human beings with $i(H. pylori) and infections of animals with bacteria belonging to the genus $i(Helicobacter) in relation thereto. The above compositions are useful in the prevention (including the prevention of recurrence) and treatment of peptic ulcers (gastric ulcer, duodenal ulcer, etc.), inflammations (acute or chronic gastritis or duodenitis), diseases in the upper part of the digestive tract (gastric cancer, etc.), mucosa-associated lymphoid tissue (MALT) lymphoma, chronic heart diseases, etc.

Inventors:
WATANABE MASATO (JP)
TANAKA KOUICHI (JP)
KOMIYA MASAYUKI (JP)
RANTIATMODJO RATNA MURNI (ID)
Application Number:
PCT/JP1998/002133
Publication Date:
November 19, 1998
Filing Date:
May 14, 1998
Export Citation:
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Assignee:
YAMANOUCHI PHARMA CO LTD (JP)
P T KALBE FARMA (ID)
WATANABE MASATO (JP)
TANAKA KOUICHI (JP)
KOMIYA MASAYUKI (JP)
RANTIATMODJO RATNA MURNI (ID)
International Classes:
A61K31/47; A61P31/04; C07D215/60; (IPC1-7): A61K31/47
Foreign References:
JPH02256665A1990-10-17
JPH05117268A1993-05-14
JPH07189A1995-01-06
Other References:
See also references of EP 0992241A4
Attorney, Agent or Firm:
Nagai, Shozo (Patent & Information Dept., 17-1, Hasune 3-chom, Itabashi-ku Tokyo, JP)
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