Title:
MEDICINAL COMPOSITIONS FOR TREATMENT OF ATRIAL FIBRILLATION
Document Type and Number:
WIPO Patent Application WO/2000/038688
Kind Code:
A1
Abstract:
Medicinal compositions for treatment of atrial fibrillation, containing compounds represented by general formula [I] or salts or prodrugs of the same [wherein R?1¿ is hydrogen or lower alkoxy; R?2¿ is hydrogen, lower alkoxy, phenyl (which may be substituted with one to three substituents selected from the group consisting of hydroxyl and lower alkoxy groups), formula [II] or formula [III] (wherein R?3¿ is acyl); X is -CO- or -CH¿2?-; and n is 1 or 2]. Methods for the treatment of atrial fibrillation with the compounds; and use of the compounds in preparing drugs for treatment of atrial fibrillation.
Inventors:
AISAKA KAZUO (JP)
IMAGAWA NAOYA (JP)
MIYAI HISATO (JP)
OGAWA SATOSHI (JP)
IMAGAWA NAOYA (JP)
MIYAI HISATO (JP)
OGAWA SATOSHI (JP)
Application Number:
PCT/JP1999/007359
Publication Date:
July 06, 2000
Filing Date:
December 27, 1999
Export Citation:
Assignee:
JAPAN TOBACCO INC (JP)
KANEKO NOBORU (JP)
AISAKA KAZUO (JP)
IMAGAWA NAOYA (JP)
MIYAI HISATO (JP)
OGAWA SATOSHI (JP)
KANEKO NOBORU (JP)
AISAKA KAZUO (JP)
IMAGAWA NAOYA (JP)
MIYAI HISATO (JP)
OGAWA SATOSHI (JP)
International Classes:
A61P9/06; C07D417/06; (IPC1-7): A61K31/554; A61P9/06
Domestic Patent References:
| WO1992012148A1 | 1992-07-23 |
Foreign References:
| EP0467325A2 | 1992-01-22 |
Other References:
See also references of EP 1147772A4
Attorney, Agent or Firm:
Takeda, Masahiko (Nagata-cho 2-chome Chiyoda-ku Tokyo, JP)
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