Title:
MEDIUM COMPOSITION FOR CULTURING URINE-DERIVED STEM CELL, METHOD FOR ISOLATING AND CULTURING URINE-DERIVED STEM CELL USING SAME, URINE-DERIVED STEM CELL WITH IMPROVED THERAPEUTIC FUNCTION FOR RENAL DISEASE, AND CELL THERAPY PRODUCT COMPOSITION CONTAINING SAME
Document Type and Number:
WIPO Patent Application WO/2023/054825
Kind Code:
A1
Abstract:
The present invention relates to a culture medium for isolating and culturing urine-derived stem cells, a method for isolating and culturing urine-derived stem cells using the culture medium, urine-derived stem cells cultured in the culture medium, and a cell therapy product composition containing same.
Inventors:
LEE HONG-KI (KR)
LEE SEONG-HUN (KR)
KIM SANG-HEON (KR)
JIN JEONG-AH (KR)
KANG TAE-WOOK (KR)
SO HYUNG-JOON (KR)
SO SU-BIN (KR)
JUNG KYU-SUNG (KR)
LEE JAE-UNG (KR)
YOON JIN-SANG (KR)
LEE YOUNG-JUN (KR)
LEE SEONG-HUN (KR)
KIM SANG-HEON (KR)
JIN JEONG-AH (KR)
KANG TAE-WOOK (KR)
SO HYUNG-JOON (KR)
SO SU-BIN (KR)
JUNG KYU-SUNG (KR)
LEE JAE-UNG (KR)
YOON JIN-SANG (KR)
LEE YOUNG-JUN (KR)
Application Number:
PCT/KR2022/005579
Publication Date:
April 06, 2023
Filing Date:
April 19, 2022
Export Citation:
Assignee:
EHLBIO CO LTD (KR)
International Classes:
C12N5/071; A61K35/22; A61K48/00; A61P13/12
Foreign References:
| KR20210053725A | 2021-05-12 | |||
| KR20150133516A | 2015-11-30 | |||
| KR20210053725A | 2021-05-12 | |||
| KR20190139702A | 2019-12-18 |
Other References:
ANDRUKHOVA OLENA; STREICHER CARMEN; ZEITZ UTE; ERBEN REINHOLD G.: "Fgf23 and parathyroid hormone signaling interact in kidney and bone", MOLECULAR AND CELLULAR ENDOCRINOLOGY, vol. 436, 4 August 2016 (2016-08-04), IE , pages 224 - 239, XP029727456, ISSN: 0303-7207, DOI: 10.1016/j.mce.2016.07.035
WEI KAI, YIN ZHIWEI, XIE YUANSHENG: "Roles of the kidney in the formation, remodeling and repair of bone", JOURNAL OF NEPHROLOGY, vol. 29, no. 3, 1 June 2016 (2016-06-01), IT , pages 349 - 357, XP093054511, ISSN: 1121-8428, DOI: 10.1007/s40620-016-0284-7
V. LAVI-MOSHAYOFF, G. WASSERMAN, T. MEIR, J. SILVER, T. NAVEH-MANY: "PTH increases FGF23 gene expression and mediates the high-FGF23 levels of experimental kidney failure: a bone parathyroid feedback loop", AJP: RENAL PHYSIOLOGY,, vol. 299, no. 4, 1 October 2010 (2010-10-01), pages F882 - F889, XP055122050, ISSN: 03636127, DOI: 10.1152/ajprenal.00360.2010
TANG YUTAO, XIA HAN, KANG LIANG, SUN QUAN, SU ZHE, HAO CONGQIANG, XUE YUAN: "Effects of Intermittent Parathyroid Hormone 1–34 Administration on Circulating Mesenchymal Stem Cells in Postmenopausal Osteoporotic Women", MEDICAL SCIENCE MONITOR, vol. 25, 1 January 2019 (2019-01-01), pages 259 - 268, XP093054514, DOI: 10.12659/MSM.913752
"Remington's Pharmaceutical Sciences", 1995, MACK PUBLISHING COMPANY
WEI KAI, YIN ZHIWEI, XIE YUANSHENG: "Roles of the kidney in the formation, remodeling and repair of bone", JOURNAL OF NEPHROLOGY, vol. 29, no. 3, 1 June 2016 (2016-06-01), IT , pages 349 - 357, XP093054511, ISSN: 1121-8428, DOI: 10.1007/s40620-016-0284-7
V. LAVI-MOSHAYOFF, G. WASSERMAN, T. MEIR, J. SILVER, T. NAVEH-MANY: "PTH increases FGF23 gene expression and mediates the high-FGF23 levels of experimental kidney failure: a bone parathyroid feedback loop", AJP: RENAL PHYSIOLOGY,, vol. 299, no. 4, 1 October 2010 (2010-10-01), pages F882 - F889, XP055122050, ISSN: 03636127, DOI: 10.1152/ajprenal.00360.2010
TANG YUTAO, XIA HAN, KANG LIANG, SUN QUAN, SU ZHE, HAO CONGQIANG, XUE YUAN: "Effects of Intermittent Parathyroid Hormone 1–34 Administration on Circulating Mesenchymal Stem Cells in Postmenopausal Osteoporotic Women", MEDICAL SCIENCE MONITOR, vol. 25, 1 January 2019 (2019-01-01), pages 259 - 268, XP093054514, DOI: 10.12659/MSM.913752
"Remington's Pharmaceutical Sciences", 1995, MACK PUBLISHING COMPANY
Attorney, Agent or Firm:
WETHEPEOPLE IP & LAW FIRM (KR)
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