MELT-GRANULATED FINGOLIMOD - RATIOPHARM GMBH

Title:

MELT-GRANULATED FINGOLIMOD

Document Type and Number:

WIPO Patent Application WO/2011/131370

Kind Code:

A8

Abstract:

The invention relates to methods including the step of joint melt processing of (i) fmgolimod or a pharmaceutically acceptable salt thereof, with (ii) a matrix former into an intermediate, intermediates obtainable in this way, and oral dosage forms, especially tablets, containing the intermediates of the invention. The invention further relates to a method of preparing the dosage forms of the invention, especially tablets. Finally, the invention relates to oral dosage forms for the treatment of multiple sclerosis.

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Inventors:

PAETZ JANA (DE)
BRUECK SANDRA (DE)

Application Number:

PCT/EP2011/002053

Publication Date:

January 10, 2013

Filing Date:

April 21, 2011

Export Citation:

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Assignee:

RATIOPHARM GMBH (DE)
PAETZ JANA (DE)
BRUECK SANDRA (DE)

International Classes:

A61K9/14; A61K9/16; A61K9/20; A61K31/00; A61K47/34; A61K47/36

Attorney, Agent or Firm:

AECHTER, Bernd (Mauerkircherstrasse 45, München, DE)

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