METAL ABSTRACTION PEPTIDE AND USES THEREOF

Title:

METAL ABSTRACTION PEPTIDE AND USES THEREOF

Document Type and Number:

WIPO Patent Application WO/2012/097344

Kind Code:

A3

Abstract:

Compositions comprising certain tripeptides which are capable of binding a metal in a square planar orientation, a square pyramidal orientation, or both, are disclosed in processes for modulating tagged peptides or proteins. Such compositions and processes may be used for site-specific chiral inversion of amino acids, site-specific peptide cleavage, and protein purification, among other uses.

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Inventors:

LAURENCE JENNIFER ANN STOWELL (US)
KRAUSE MARY ELIZABETH (US)
JACKSON TIMOTHY A (US)
LAURENCE GEORGE (US)

Application Number:

PCT/US2012/021382

Publication Date:

October 26, 2012

Filing Date:

January 13, 2012

Export Citation:

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Assignee:

UNIV KANSAS (US)
ECHOGEN INC (US)
LAURENCE JENNIFER ANN STOWELL (US)
KRAUSE MARY ELIZABETH (US)
JACKSON TIMOTHY A (US)
LAURENCE GEORGE (US)

International Classes:

C07K5/08; A61K38/06; C07K1/14

Foreign References:

US20100221839A1	2010-09-02
US7799561B2	2010-09-21
US7741053B2	2010-06-22
US7033520B2	2006-04-25

Other References:

KRAUSE, M. E. ET AL., INORG. CHEM., vol. 49, 12 September 2009 (2009-09-12), pages 362 - 364

Attorney, Agent or Firm:

ALEMOZAFAR, Ali et al. (650 Page Mill RoadPalo Alto, CA, US)

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