Title:
METAL COMPLEX INCLUDING TRIDENTATE AMINODICARBENE LIGAND AND HYDROGENATION REDUCTION METHOD USING SAME
Document Type and Number:
WIPO Patent Application WO/2014/203963
Kind Code:
A1
Abstract:
By using a metal complex including a ruthenium ion or an osmium ion and a tridentate aminodicarbene ligand that includes one secondary amine group and two specific heterocyclic carbene groups sandwiching the amine group, it is possible to subject, for example, carbonyl compounds, such as ketones, carboxylic acid esters, lactones, carboxylic acid amides, and lactams, and imines to hydrogenation reduction under relatively mild conditions, and produce corresponding alcohols and amines with high yield and high catalytic efficiency. This metal complex is obtained by a method comprising a step for reacting a specific aminodicarbene precursor with a specific metal compound and then with a specific compound. It is possible to subject a carbonyl compound or an imine to hydrogenation reduction by reducing the carbonyl compound or the imine by using a hydrogen donor in the presence of said metal complex.
Inventors:
MURATA YUSUKE (JP)
TORIHARA MASAHIRO (JP)
TORIHARA MASAHIRO (JP)
Application Number:
PCT/JP2014/066268
Publication Date:
December 24, 2014
Filing Date:
June 19, 2014
Export Citation:
Assignee:
KURARAY CO (JP)
International Classes:
C07F15/00; B01J31/24; C07C29/145; C07C29/149; C07C31/125; C07C31/20; C07C33/22; C07B61/00
Domestic Patent References:
| WO2013023307A1 | 2013-02-21 | |||
| WO2013024119A1 | 2013-02-21 | |||
| WO2011048727A1 | 2011-04-28 | |||
| WO2012052996A2 | 2012-04-26 | |||
| WO2010114137A1 | 2010-10-07 | |||
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Foreign References:
| US20120253042A1 | 2012-10-04 | |||
| JP2010527316A | 2010-08-12 | |||
| JP2008538352A | 2008-10-23 | |||
| JP2008537946A | 2008-10-02 |
Other References:
POYATOS ET AL.: "New ruthenium (II) CNC-pincer bis (carbene) complexes: synthesis and catalytic activity", ORGANOMETALLICS, vol. 22, no. 5, 3 March 2003 (2003-03-03), pages 1110 - 1114, XP001144354, DOI: 10.1021/OM020817W
HERNANDEZ-JUAREZ ET AL.: "Hydrogenation of imines catalysed by ruthenium (II) complexes based on lutidine-derived CNC pincer ligands", DALTON TRANSACTIONS, vol. 42, no. 2, 14 January 2013 (2013-01-14), pages 351 - 354, XP055305738, DOI: 10.1039/C2DT31907A
SONG, D. ET AL., CHEMICAL COMMUNICATIONS, vol. 47, 2011, pages 8349 - 8351
"Protective Groups in Organic Synthesis", 1991, JOHN WILEY & SONS, INC.
ANGEW. CHEM. INT. ED, vol. 51, 2012, pages 2772 - 2775
WANZHI CHEN ET AL., ORGANOMETALLICS, vol. 31, 2012, pages 282 - 288
HERNANDEZ-JUAREZ ET AL.: "Hydrogenation of imines catalysed by ruthenium (II) complexes based on lutidine-derived CNC pincer ligands", DALTON TRANSACTIONS, vol. 42, no. 2, 14 January 2013 (2013-01-14), pages 351 - 354, XP055305738, DOI: 10.1039/C2DT31907A
SONG, D. ET AL., CHEMICAL COMMUNICATIONS, vol. 47, 2011, pages 8349 - 8351
"Protective Groups in Organic Synthesis", 1991, JOHN WILEY & SONS, INC.
ANGEW. CHEM. INT. ED, vol. 51, 2012, pages 2772 - 2775
WANZHI CHEN ET AL., ORGANOMETALLICS, vol. 31, 2012, pages 282 - 288
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
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