Title:
METAL-NUCLEIC ACID NANOPARTICLE, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/087867
Kind Code:
A1
Abstract:
A metal-nucleic acid nanoparticle is a nanoparticle having a spherical structure formed by combining a metal ion and a nucleic acid by means of coordination. The preparation method comprises adding a metal ion solution to a nucleic acid solution, vortexing the mixture, and heating, centrifuging, washing and resuspending the mixture, so as to obtain the metal-nucleic acid nanoparticle. The nanoparticle can be used for preparing a drug delivery system and a biological detection reagent.
Inventors:
LI LELE (CN)
WANG CONGLI (CN)
DI ZHENGHAN (CN)
WANG CONGLI (CN)
DI ZHENGHAN (CN)
Application Number:
PCT/CN2019/081244
Publication Date:
May 07, 2020
Filing Date:
April 03, 2019
Export Citation:
Assignee:
NAT CT NANOSCIENCE & TECHNOLOGY CHINA (CN)
International Classes:
C12N15/87; A61P35/00; C07F15/02; C07H21/00; C12N15/11; C12Q1/68
Foreign References:
| CN107074767A | 2017-08-18 | |||
| CN102872463A | 2013-01-16 |
Attorney, Agent or Firm:
BEYOND ATTORNEYS AT LAW (CN)
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