Title:
METHIONINE ADENOSINE TRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/169554
Kind Code:
A1
Abstract:
Provided in the present application are a methionine adenosine transferase inhibitor, a pharmaceutical composition containing same, and the use thereof. The compound of the present application has excellent MAT2a enzyme inhibitory activity, and also has an excellent inhibitory effect on the growth of cancer cells, so that the compound of the present application can have an excellent therapeutic effect on MAT2a-related cancers or tumor diseases.
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Inventors:
DONG LIJIN (CN)
YI TAO (CN)
HU KAI (CN)
TIAN LIN (CN)
ZHANG YI (CN)
TANG YUANQING (CN)
ZHANG XIAODONG (CN)
TANG JUN (CN)
YI TAO (CN)
HU KAI (CN)
TIAN LIN (CN)
ZHANG YI (CN)
TANG YUANQING (CN)
ZHANG XIAODONG (CN)
TANG JUN (CN)
Application Number:
PCT/CN2023/080740
Publication Date:
September 14, 2023
Filing Date:
March 10, 2023
Export Citation:
Assignee:
SCINNOHUB PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D471/04; A61K31/4375; A61K31/495; A61K31/4985; A61K31/519; A61P35/00; C07D471/00
Domestic Patent References:
| WO2022052924A1 | 2022-03-17 | |||
| WO2020243376A1 | 2020-12-03 | |||
| WO2021139775A1 | 2021-07-15 |
Foreign References:
| CN111936499A | 2020-11-13 | |||
| CN113454085A | 2021-09-28 | |||
| CN113474347A | 2021-10-01 |
Attorney, Agent or Firm:
BEIJING SUNHOPE INTELLECTUAL PROPERTY LTD. et al. (CN)
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