Title:
METHOD OF ACCELERATING DIFFERENTIATION OF STEM CELLS FROM APICAL PAPILLA BY USING OPTICAL STIMULATION
Document Type and Number:
WIPO Patent Application WO/2021/221199
Kind Code:
A1
Abstract:
The present invention relates to a technique for accelerating differentiation of stem cells from apical papilla (SCAP) by using an optical stimulation. More specifically, the present invention provides a composition, kit, and method for tooth transplantation or dental root formation, comprising SCAP irradiated with near-infrared radiation, and a method for differentiating SCAP, comprising a step of irradiating SCAP with near-infrared radiation.
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Inventors:
KIM HONG BAE (KR)
CHOUNG PILL-HOON (KR)
CHUNG JONG HOON (KR)
KANG MOON HO (KR)
CHOUNG PILL-HOON (KR)
CHUNG JONG HOON (KR)
KANG MOON HO (KR)
Application Number:
PCT/KR2020/005637
Publication Date:
November 04, 2021
Filing Date:
April 28, 2020
Export Citation:
Assignee:
SEOUL NAT UNIV R&DB FOUNDATION (KR)
International Classes:
A61L27/38; A61C8/02; A61N5/06; C12M1/42; C12N5/074
Foreign References:
| KR101859683B1 | 2018-07-02 | |||
| KR101212548B1 | 2012-12-14 |
Other References:
KIM HONG BAE, BAIK KU YOUN, SEONWOO HOON, JANG KYOUNG-JE, LEE MYUNG CHUL, CHOUNG PILL-HOON, CHUNG JONG HOON: "Effects of pulsing of light on the dentinogenesis of dental pulp stem cells in vitro", SCIENTIFIC REPORTS, vol. 8, no. 1, 2057, 1 December 2018 (2018-12-01), pages 1 - 11, XP055862381, DOI: 10.1038/s41598-018-19395-x
KIM HONG BAE, BAIK KU YOUN, CHOUNG PILL-HOON, CHUNG JONG HOON: "Pulse frequency dependency of photobiomodulation on the bioenergetic functions of human dental pulp stem cells", SCIENTIFIC REPORTS, vol. 7, no. 1, 15927, 1 December 2017 (2017-12-01), pages 1 - 12, XP055862383, DOI: 10.1038/s41598-017-15754-2
IVANA MARIA ZACCARA, LETÍCIA BOLDRIN MESTIERI, MARIA STELLA MOREIRA, FABIANA SOARES GRECCA, MANOELA DOMINGUES MARTINS, PATRÍCIA MA: "Photobiomodulation therapy improves multilineage differentiation of dental pulp stem cells in three-dimensional culture model", JOURNAL OF BIOMEDICAL OPTICS, vol. 23, no. 9, 10 September 2018 (2018-09-10), pages 1 - 9, XP055862387, DOI: 10.1117/1.JBO.23.9.095001
KIM HONG BAE, BAIK KU YOUN, CHOUNG PILL-HOON, CHUNG JONG HOON: "Pulse frequency dependency of photobiomodulation on the bioenergetic functions of human dental pulp stem cells", SCIENTIFIC REPORTS, vol. 7, no. 1, 15927, 1 December 2017 (2017-12-01), pages 1 - 12, XP055862383, DOI: 10.1038/s41598-017-15754-2
IVANA MARIA ZACCARA, LETÍCIA BOLDRIN MESTIERI, MARIA STELLA MOREIRA, FABIANA SOARES GRECCA, MANOELA DOMINGUES MARTINS, PATRÍCIA MA: "Photobiomodulation therapy improves multilineage differentiation of dental pulp stem cells in three-dimensional culture model", JOURNAL OF BIOMEDICAL OPTICS, vol. 23, no. 9, 10 September 2018 (2018-09-10), pages 1 - 9, XP055862387, DOI: 10.1117/1.JBO.23.9.095001
Attorney, Agent or Firm:
YOU ME PATENT AND LAW FIRM (KR)
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