Title:
METHOD AND ANALYTICAL INSTRUMENT FOR INTEGRATED ANALYSIS OF N-LINKED AND O-LINKED GLYCOPEPTIDES
Document Type and Number:
WIPO Patent Application WO/2023/177035
Kind Code:
A1
Abstract:
This method for the integrated analysis of N-linked and O-linked glycopeptides comprises the steps in which an analytical instrument: receives mass spectrum data of a sample; selects only glycopeptide spectrum data by using tandem spectrum (MS/MS) data extracted from the mass spectrum data; identifies an N-linked glycopeptide and an O-linked glycopeptide from the glycopeptide spectrum data; and determines sugar chain modification on the basis of the peak values of predetermined candidate peaks for each of the N-linked glycopeptide or the O-linked glycopeptide.
Inventors:
PARK GUN WOOK (KR)
LEE NAM YONG (KR)
KIM KWANG HOE (KR)
LEE SANG YONG (KR)
LEE NAM YONG (KR)
KIM KWANG HOE (KR)
LEE SANG YONG (KR)
Application Number:
PCT/KR2022/015501
Publication Date:
September 21, 2023
Filing Date:
October 13, 2022
Export Citation:
Assignee:
CELLKEY INC (KR)
International Classes:
G01N33/68; G01N27/62
Foreign References:
| KR20190035325A | 2019-04-03 | |||
| CN112326770A | 2021-02-05 | |||
| KR20120125889A | 2012-11-19 | |||
| US20130069645A1 | 2013-03-21 | |||
| KR102447238B1 | 2022-09-27 |
Other References:
LIU GANG, KAI CHENG, CHI Y. LO, JUN LI, JUN QU AND SRIRAM NEELAMEGHAM: "A Comprehensive, Open-source Platform for Mass Spectrometry-based Glycoproteomics Data Analysis", MOLECULAR & CELLULAR PROTEOMICS, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, vol. 16, no. 11, 1 January 2017 (2017-01-01), US , pages 2032 - 20247, XP093089790, ISSN: 1535-9476
Attorney, Agent or Firm:
ISIS IP LAW LLC (KR)
Download PDF:
Previous Patent: CONTROLLER-INTEGRATED STATIC ELECTRICITY MEASUREMENT APPARATUS
Next Patent: PORTABLE STEREOSCOPIC CAMERA AND SYSTEM
Next Patent: PORTABLE STEREOSCOPIC CAMERA AND SYSTEM