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Title:
METHOD FOR ANALYZING ROOT-BARK OF CHINESE WOLFBERRY COMPOUND STRUCTURE BY MOLECULAR NETWORKING
Document Type and Number:
WIPO Patent Application WO/2021/047394
Kind Code:
A1
Abstract:
A method for analyzing a root-bark of Chinese wolfberry compound structure by molecular networking, comprising steps such as selection of a chemical reagent and a material, selection of a medicinal material, sample pre-treatment, and HPLC-MS/MS networking analysis. A liquid chromatography-mass spectrometry method is also used to discover the structures of five new compounds in the root-bark of Chinese wolfberry, and the mass spectrometry fragmentation laws of the compounds. The method for analyzing a root-bark of Chinese wolfberry compound structure by molecular networking facilitates discovering new structural analogs in the root-bark of Chinese wolfberry, analyzing new structures, discovering microconstituents in traditional Chinese medicine, understanding the effect mechanism of traditional Chinese medicine at the molecular level, and accelerating the development of modernization of traditional Chinese medicine.

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Inventors:
JIANG ZHIBO (CN)
CHEN YONGXIN (CN)
CHEN JINGZHI (CN)
XIANG WENJUAN (CN)
GUO XIN (CN)
MA BINGZHEN (CN)
LI CHONGLONG (CN)
FANG HUAN (CN)
TANG YONGHONG (CN)
MA XIAOLI (CN)
Application Number:
PCT/CN2020/111606
Publication Date:
March 18, 2021
Filing Date:
August 27, 2020
Export Citation:
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Assignee:
NORTH MINZU UNIV (CN)
International Classes:
G01N30/88
Foreign References:
CN110531017A2019-12-03
CN110157724A2019-08-23
CN102749299A2012-10-24
JP2006294014A2006-10-26
CN109932446A2019-06-25
CN105758977A2016-07-13
CN109439705A2019-03-08
CN108484428A2018-09-04
Other References:
BRATTAIN LAURA J.; TELFER BRIAN A.; DHYANI MANISH; GRAJO JOSEPH R.; SAMIR ANTHONY E.: "Machine learning for medical ultrasound: status, methods, and future opportunities", ABDOMINAL RADIOLOGY, SPRINGER US, NEW YORK, vol. 43, no. 4, 28 February 2018 (2018-02-28), New York, pages 786 - 799, XP036472474, ISSN: 2366-004X, DOI: 10.1007/s00261-018-1517-0
Attorney, Agent or Firm:
MERITS & TREE (CN)
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