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Title:
METHOD AND ANTIGEN COMPOSITION FOR RAPID DETECTION OF CHAGAS DISEASE, LEISHMANIASIS, AND HEARTWORM IN HUMANS AND ANIMALS
Document Type and Number:
WIPO Patent Application WO/2023/077043
Kind Code:
A3
Abstract:
Among several illnesses common to pets such as dogs that can also affect humans, American trypanosomiasis, commonly known as Chagas disease, is a parasitic 20 condition caused by the hemoflagellated protozoa, Trypanosoma cruzi. Active transmission is through triatomine vectors known as kissing bugs, which are prevalent in North and South America. Diagnostic methods, systems, test strips, test kits, and other immunoassay materials are provided for the detection of antibodies to one or more specific parasites of veterinary and human concern in biological samples, including those that are responsible for Chagas disease (Trypanosoma cruzi), Leishmaniasis (Leishmania infantum), and Heartworm (Dirofilaria immitis).

Inventors:
PANIZ-MONDOLFI ALBERTO (US)
Application Number:
PCT/US2022/078838
Publication Date:
September 07, 2023
Filing Date:
October 28, 2022
Export Citation:
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Assignee:
VIDA PHARMACAL INC (US)
International Classes:
A61K39/005; A61K39/008; C07K16/20; G01N33/569
Domestic Patent References:
WO1999005528A11999-02-04
Foreign References:
US20030108960A12003-06-12
US20080031878A12008-02-07
US6150135A2000-11-21
Other References:
DATABASE Protein [online] NCBI; 30 May 2018 (2018-05-30), ANONYMOUS : "hypothetical protein C3747_25g103 [Trypanosoma cruzi]", XP093098070, Database accession no. PMV16076
SEWID ALAA H., HASSAN M. NABIL, AMMAR A. M., BEMIS DAVID A., KANIA STEPHEN A.: "Staphylococcus pseudintermedius Sbi paralogs inhibit complement and bind IgM, IgG Fc and Fab", PLOS ONE, vol. 14, no. 7, 23 July 2019 (2019-07-23), pages 1 - 16, XP093090584, DOI: 10.1371/journal.pone.0219817
Attorney, Agent or Firm:
SCHULMAN, B. Aaron (US)
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