Title:
METHOD AND APPARATUS FOR ANALYZING BIOMOLECULES
Document Type and Number:
WIPO Patent Application WO/2017/212647
Kind Code:
A1
Abstract:
The purpose of the invention is to provide a method for analyzing biomolecules with which it is possible to easily suppress the occlusion of nanopores. The first embodiment of the invention is a method for analyzing biomolecules including a step for preparing a substrate having nanopores, a step for placing a sample solution including biomolecules and at least one compound (A) selected from the group consisting of primary amines, secondary amines, guanidine compounds, and salts thereof on the substrate, and a step for detecting the changes in light or electrical signal generated when the biomolecules pass through the nanopores.
Inventors:
FUJIOKA MICHIRU (JP)
GOTO YUSUKE (JP)
YOKOI TAKAHIDE (JP)
GOTO YUSUKE (JP)
YOKOI TAKAHIDE (JP)
Application Number:
PCT/JP2016/067406
Publication Date:
December 14, 2017
Filing Date:
June 10, 2016
Export Citation:
Assignee:
HITACHI HIGH TECH CORP (JP)
International Classes:
G01N27/00; C12Q1/68; G01N27/28; G01N27/416; G01N27/447; G01N33/483
Domestic Patent References:
| WO2013021815A1 | 2013-02-14 |
Foreign References:
| JP2016057263A | 2016-04-21 | |||
| JP2009515169A | 2009-04-09 |
Other References:
WINTERS-HILT STEPHEN ET AL.: "Nanopore-based kinetics analysis of individual antibody- channel and antibody-antigen interactions", BMC BIOINFORMATICS, vol. 8, no. 7, 2007, pages 20, XP021027678
Attorney, Agent or Firm:
HIRAKI Yusuke et al. (JP)
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