Title:
METHOD AND APPARATUS FOR PROTEIN MANIPULATION
Document Type and Number:
WIPO Patent Application WO2002044327
Kind Code:
A9
Abstract:
A method and apparatus for extracting, identifying, and manipulating proteins or peptides from a solution uses paramagnetic beads having a coating with an affinity for the target component. In one embodiment, paramagnetic beads coated with C18 are used to adsorb proteins and peptides. The beads can be used to purify, immobilize and assay antibodies. By cycling the beads, many times greater molar amount of binding partner may be separated from a solution. A magnetic probe is used to capture the beads and transfer the beads to selected processing stages.
Inventors:
ANDERSON N LEIGH (US)
Application Number:
PCT/US2001/044269
Publication Date:
August 28, 2003
Filing Date:
November 28, 2001
Export Citation:
Assignee:
LARGE SCALE PROTEOMICS CORP (US)
ANDERSON N LEIGH (US)
ANDERSON N LEIGH (US)
International Classes:
G01N33/553; B01D43/00; B01D57/00; B03C1/00; B03C1/28; C07K1/22; C07K1/24; C07K1/36; C07K17/08; C07K17/14; (IPC1-7): G01N33/553; G01N27/00; G01N33/53; G01N33/558
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