Title:
METHOD FOR ASSAYING ACRYLAMIDE IN COATING PRODUCT
Document Type and Number:
WIPO Patent Application WO/2023/035293
Kind Code:
A1
Abstract:
A method for assaying acrylamide in a coating product, comprising the following steps: crushing a coating product; extracting the crushed coating product using a first extractant to obtain a first extract liquid; sequentially performing bromination derivative treatment, bromine removal treatment and centrifugation treatment on the first extraction liquid, and collecting a supernatant; extracting the supernatant using a second extractant to obtain a second extract liquid; purifying and concentrating the second extract to obtain a sample solution to be tested; and assaying acrylamide content in the sample solution to be tested. By means of generating 2,3-dibromopropionamide from an acrylamide bromination reaction, polarity and solubility are changed. An organic phase is collected, which facilitates purification treatment and increases a recovery rate. By means of further purification and concentration, an impurity peak is reduced, and the detection limit is lowered. Finally, when using a gas chromatograph having an electron capture detector for assaying, 2,3-dibromopropionamide has a higher response value on the electron capture detector and has higher sensitivity.
Inventors:
CHEN ZHAOJING (CN)
LIU PENG (CN)
SUN HUILING (CN)
CHENG TINGTING (CN)
GAO GUANJUN (CN)
HUANG DEYI (CN)
LI KEXIANG (CN)
XUE JIE (CN)
LI QIAN (CN)
MA ZHANKUI (CN)
WANG TENG (CN)
ZHANG ZHENGCHAO (CN)
LIU PENG (CN)
SUN HUILING (CN)
CHENG TINGTING (CN)
GAO GUANJUN (CN)
HUANG DEYI (CN)
LI KEXIANG (CN)
XUE JIE (CN)
LI QIAN (CN)
MA ZHANKUI (CN)
WANG TENG (CN)
ZHANG ZHENGCHAO (CN)
Application Number:
PCT/CN2021/118390
Publication Date:
March 16, 2023
Filing Date:
September 15, 2021
Export Citation:
Assignee:
SHANDONG ACADEMY OF ENV SCIENCES CO LTD (CN)
SHANDONG ACADEMY OF ENV SCIENCES ENV TESTING CO LTD (CN)
SHANDONG ACADEMY OF ENV SCIENCES ENV TESTING CO LTD (CN)
International Classes:
G01N30/02; G01N30/06; G01N30/88
Foreign References:
| CN111289673A | 2020-06-16 | |||
| CN111257455A | 2020-06-09 | |||
| CN107356683A | 2017-11-17 |
Other References:
ALAIN, P. ET AL.: "Trace level determination of acrylamide in cereal-based foods by gas chromatography-mass spectrometry", JOURNAL OF CHROMATOGRAPHY A, vol. 1035, no. 1, 30 April 2004 (2004-04-30), XP004500718, ISSN: 0021-9673, DOI: 10.1016/j.chroma.2004.02.037
WANG JIYANG: "Study on Determination of Acrylamide in Water by Gas Chromatography", WATER TECHNOLOGY, vol. 14, no. 4, 31 August 2020 (2020-08-31), pages 55 - 57, XP093045201, ISSN: 1673-9353, DOI: 10.3969/j.issn.1673-9353.2020.04.013
YANG SICHAO, ZHANG HUI, WANG JUNHAN, CHEN FANG: "Quantification of acrylamide in foods by gas chromatography-mass spectrometry coupled with pro-column derivatization", SEPU - CHINESE JOURNAL OF CHROMATOGRAPHY, HUAXUE ZAZHI CHUBANSHE, DALIAN, CN, vol. 29, no. 5, 4 July 2011 (2011-07-04), CN , pages 404 - 408, XP093045203, ISSN: 1000-8713, DOI: 10.3724/SP.J.1123.2011.00404
WANG JIYANG: "Study on Determination of Acrylamide in Water by Gas Chromatography", WATER TECHNOLOGY, vol. 14, no. 4, 31 August 2020 (2020-08-31), pages 55 - 57, XP093045201, ISSN: 1673-9353, DOI: 10.3969/j.issn.1673-9353.2020.04.013
YANG SICHAO, ZHANG HUI, WANG JUNHAN, CHEN FANG: "Quantification of acrylamide in foods by gas chromatography-mass spectrometry coupled with pro-column derivatization", SEPU - CHINESE JOURNAL OF CHROMATOGRAPHY, HUAXUE ZAZHI CHUBANSHE, DALIAN, CN, vol. 29, no. 5, 4 July 2011 (2011-07-04), CN , pages 404 - 408, XP093045203, ISSN: 1000-8713, DOI: 10.3724/SP.J.1123.2011.00404
Attorney, Agent or Firm:
BEIJING IPLING INTELLECTUAL PROPERTY LAW FIRM (CN)
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