Title:
METHOD BY WHICH BIOSENSOR DEVICE DETECTS ANTIGEN BY USING MULTIPLE FREQUENCIES
Document Type and Number:
WIPO Patent Application WO/2022/145976
Kind Code:
A1
Abstract:
The present invention provides a method by which a biosensor device detects an antigen by using multiple frequencies, the method enabling an antigen to be detected with high sensitivity. A method by which a biosensor device detects an antigen by using multiple frequencies, according to one embodiment of the present invention, comprises the steps of: loading an antibody in the biosensor device including a micro-well that has an action electrode and a counterpart electrode disposed therein; measuring the impedance of the antibody for each of a first frequency and a second frequency; performing an antigen-antibody reaction by injecting an antigen into the biosensor device; using the first frequency and the second frequency to measure the impedances of each of the antigen and the antibody that are bound by means of the antigen-antibody reaction; and calculating changes in impedance that result from the antigen-antibody reaction from the impedances of the antigen and the antibody for the first frequency and the impedances of the antigen and the antibody for the second frequency.
Inventors:
SHIN KYEONG SIK (KR)
KANG JI YOON (KR)
KANG JI YOON (KR)
Application Number:
PCT/KR2021/020058
Publication Date:
July 07, 2022
Filing Date:
December 28, 2021
Export Citation:
Assignee:
BIOXONICS CO LTD (KR)
International Classes:
G01N33/543; G01N27/02; G01N27/07; G01N27/08
Foreign References:
| KR20200137666A | 2020-12-09 | |||
| JP2006112976A | 2006-04-27 | |||
| KR20200038844A | 2020-04-14 | |||
| KR20120028361A | 2012-03-22 | |||
| KR20160034434A | 2016-03-30 |
Attorney, Agent or Firm:
POLARIS INTERNATIONAL PATENT & LAW FIRM (KR)
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