Title:
METHOD FOR CAPTURING TARGET SUBSTANCE, SOLID-PHASE CARRIER FOR CAPTURING TARGET SUBSTANCE, AND METHOD FOR PRODUCING SOLID-PHASE CARRIER
Document Type and Number:
WIPO Patent Application WO/2015/119288
Kind Code:
A1
Abstract:
Provided are: a solid-phase carrier that has extremely low non-specific adsorption of biological substances such as proteins, peptides, nucleic acids and cells, and is capable of maintaining the activity of bound ligands at a high level; and a method for capturing a target substance using said solid-phase carrier. The method for capturing a target substance is characterized by comprising: a step for preparing a solid-phase carrier for capturing a target substance, said carrier having a base material, at least a portion of the surface thereof being formed of or coated with saccharides, and having a linker of 5-100 atoms having a reactive functional group for binding ligands that specifically bind to the target substance, wherein the saccharides are chemically bound to the linker; a step for binding the ligands to the solid-phase carrier to obtain a solid-phase carrier having ligands bound thereto; and a step for bringing the solid-phase carrier having the ligands bound thereto into contact with a sample containing the target substance that specifically bind to the ligands.
Inventors:
KAI HIROKAZU (JP)
TAKAMOTO EIJI (JP)
TAMORI KOUJI (JP)
TAKAMOTO EIJI (JP)
TAMORI KOUJI (JP)
Application Number:
PCT/JP2015/053638
Publication Date:
August 13, 2015
Filing Date:
February 10, 2015
Export Citation:
Assignee:
JSR CORP (JP)
JSR LIFE SCIENCES CORP (JP)
JSR LIFE SCIENCES CORP (JP)
International Classes:
G01N33/543; G01N33/553
Domestic Patent References:
| WO1990015666A1 | 1990-12-27 | |||
| WO2006123686A1 | 2006-11-23 | |||
| WO2009116309A1 | 2009-09-24 | |||
| WO2005037881A1 | 2005-04-28 | |||
| WO2005037881A1 | 2005-04-28 | |||
| WO2004025297A1 | 2004-03-25 |
Foreign References:
| JP2003509034A | 2003-03-11 | |||
| JP2013011479A | 2013-01-17 | |||
| JP2000351814A | 2000-12-19 | |||
| JP2007085929A | 2007-04-05 | |||
| JPS5724369B2 | 1982-05-24 | |||
| JPS61215602A | 1986-09-25 | |||
| JPS61215603A | 1986-09-25 | |||
| JPS61215604A | 1986-09-25 | |||
| JPH10270233A | 1998-10-09 |
Other References:
J. POLYM. SCI., POLYMER LETTER ED., vol. 21, 1963, pages 937
JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS, vol. 12, 1986, pages 349 - 354
JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS, vol. 12, 1986, pages 349 - 354
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
Patent business corporation Alga patent firm (JP)
Patent business corporation Alga patent firm (JP)
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